Dairy cow management may benefit from plant nucleic acids - testing microRNAs from milk and meadowgrass wildflower, Heal-All or Selfheal - Prunella vulgaris

奶牛管理可能受益于植物核酸 - 测试来自牛奶和草地早熟禾野花、Heal-All 或 Selfheal - 夏枯草的 microRNA

• 批准号: 507779-2017
• 负责人: Altosaar, Illimar
• 金额: $ 1.68万
• 依托单位: University of Ottawa
• 依托单位国家: 加拿大
• 项目类别: Engage Grants Program
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=640229
• 关键词: Dairy; cow; management; may; benefit

Udder Comfort is a company that develops creams and sprays to better manage farm animals. The main ingredient in their products is essential oils, namely terpinen-4-ol. Udder Comfort is looking to diversify and innovate its product offerings, with the goal of optimizing animal well being. They are looking to supplement their products with additional modulators, such as Ribo-Nucleic Acids, namely microRNA (miRNA). miRNAs are small, non-coding RNAs that regulate gene expression post-transcriptionally. miRNAs are involved in multiple biological processes and are important in immune response regulation. It is possible that miRNAs are present in Udder Comfort's products, therefore Udder Comfort products and ingredients will be surveyed for the presence of miRNAs. In addition, beneficial miRNAs found in bovine milk will be added to Udder Comfort's products and tested for efficacy. Supplementing their products with additional ingredients could allow for better management, higher quality dairy products, and higher profits for farmers. Skin lotions globally already use extracts from the mint plant, citrus, and tea tree but Ontario's meadowgrass wildflower, Heal-All or also called Selfheal - Prunella vulgaris - has not been studied for effector molecules such as micro ribonucleic acid sequences (miRNA).

Udder Comfort 是一家开发乳霜和喷雾剂以更好地管理农场动物的公司。他们产品的主要成分是精油，即terpinen-4-ol。 Udder Comfort 正在寻求产品多样化和创新，以优化动物福祉。他们正在寻求用额外的调节剂来补充他们的产品，例如核糖核酸，即 microRNA (miRNA)。 miRNA 是小型非编码 RNA，可在转录后调节基因表达。 miRNA 参与多种生物过程，并且在免疫反应调节中发挥重要作用。 Udder Comfort 的产品中可能存在 miRNA，因此将调查 Udder Comfort 产品和成分中是否存在 miRNA。此外，牛奶中发现的有益 miRNA 将被添加到 Udder Comfort 的产品中并测试功效。在他们的产品中添加额外的成分可以实现更好的管理，提供更高质量的乳制品，并为农民带来更高的利润。全球护肤乳液已使用薄荷植物、柑橘和茶树的提取物，但尚未对安大略草甸野花 Heal-All 或也称为 Selfheal - 夏枯草 (Prunella vulgaris) 的提取物进行研究，以了解微核糖核酸序列 (miRNA) 等效应分子。