The timing of nutrient uptake in the Chinook salmon intestine.

加拿大是不断发展的水产养殖业的领导者，为我们的经济增加了30多亿美元（加拿大水产养殖业联盟）。鲑鱼养殖占该产业的60%。虽然大西洋鲑鱼目前在加拿大的生产中占主导地位，但由于其较高的市场价格，以及对疾病和寄生虫的抵抗力，奇努克鲑鱼等太平洋鲑鱼品种对生产者的吸引力越来越大。我们与黄岛水产养殖有限公司（YIAL）合作，该公司是加拿大最古老的太平洋鲑鱼养殖场之一，自1985年以来一直为市场生产优质有机奇努克鲑鱼。YIAL面临的一个主要问题是如何优化产品数量和产品质量，同时最大限度地降低饲料成本，这是鲑鱼养殖场运营成本的主要组成部分。鱼类和所有动物一样，拥有与生俱来的24小时周期，它们在最活跃的特定时间进食和消化食物。这些日常活动的循环被称为昼夜节律，这一主题的发现获得了2017年诺贝尔生理学奖的认可。我们的实验室研究消化道的昼夜节律，我们建议研究奇努克鲑鱼肠道的昼夜节律，以帮助优化鲑鱼的生产。为此，我们将首先测试不同品系和不同阶段的奇努克鲑的消化活性，以找出一天中消化能力最高的时间，以及哪些种群的消化道效率最高。这些实验将使饲料和库存与营养吸收的最佳时间保持一致，从而降低饲料成本和浪费。为了yal的利益，我们的项目将特别关注奇努克鲑鱼，然而，我们的工作将很容易转移到加拿大的许多其他水产养殖者身上。

Canada is a leader in a growing aquaculture industry, that adds over $3 billion to our economy (CanadianAquaculture Industry Alliance). Salmon aquaculture claims ~60% of this industry. Although Atlantic salmoncurrently dominates Canadian production, Pacific salmon species such as Chinook salmon are increasinglyattractive to producers given their higher market price, and resistance to diseases and parasites. We arepartnering with Yellow Island Aquaculture Limited (YIAL), one of Canada's oldest Pacific salmon farms thathas produced premium organic Chinook salmon for market since 1985. A major question for YIAL, is how tooptimize product quantity and product quality while minimizing feed costs, a primary component of salmonfarm operating costs. Fish, like all animal species, possess innate 24 hour cycles, and they feed and digest foodat specific times when they are most active. These cycles of daily activity are called Circadian Rhythms, a topicwhose discovery was recognized by the Nobel Prize in Physiology, 2017. Our lab studies the circadian rhythmsof the digestive tract, and we propose to study the circadian rhythms of the Chinook salmon intestine to helpYIAL optimize salmon production. To do this we will first test different strains and stages of Chinook salmonfor digestive activity, to find at what time of day digestion is highest, and which stocks have the highestdigestive tract efficiency. These experiments will enable feedings and stocks to be aligned with the optimaltime of nutrient uptake, thus reducing feed cost and waste. Our project will specifically concern Chinooksalmon for the benefit of YIAL, however, our work will be easily transferable to benefit many otheraquaculture producers in Canada.