Interactions between cells and extracellular matrix in the epithelial-mesenchymal transition of the ovarian follicular stratified epithelium

卵巢滤泡复层上皮上皮-间质转化中细胞与细胞外基质的相互作用

• 批准号: DP110102979
• 负责人: Prof Raymond Rodgers
• 金额: $ 20.06万
• 依托单位: The University of Adelaide
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP110102979
• 关键词: Interactions; between; cells; extracellular; matrix

The lining of many mammalian organs and cavities contain cells that can transform into different cells to bring about organ development or repair but if it goes horribly wrong the cells become metastatic cancers. This project examines the key features of this process especially the roles of matrix that develops around the cells in this process.

许多哺乳动物器官和洞穴的内层含有细胞，这些细胞可以转化为不同的细胞，从而实现器官的发育或修复，但如果出现严重的错误，这些细胞就会成为转移性癌症。该项目研究了这一过程的关键特征，特别是细胞周围形成的基质在这一过程中的作用。