Application of mechanical testing protocols for bioprinted tissue grafts

生物打印组织移植物机械测试方案的应用

• 批准号: 515596-2017
• 负责人: Wilson, David
• 金额: $ 0.9万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Engage Plus Grants Program
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=640374
• 关键词: Application; mechanical; testing; protocols; bioprinted

Aspect Biosystems Ltd. ("Aspect") is a Vancouver-based biotechnology company pioneering the developmentand commercialization of novel 3D bioprinting technology. Bioprinting meniscal tissue is an application ofAspect's technology with substantial potential for clinical application. The goal of this project is to applymechanical testing protocols using the Mach-1TM mechanical test system (Biomomentum, Laval, Quebec) tosuccessive iterations of bioprinted meniscal grafts. These protocols, developed under our original Engageapplication, will determine the suture pull-out strength, tensile strength, and compressive stiffness of themeniscal grafts. This is a critical step in the development of a successful meniscal graft.

Factive Biosystems Ltd.（“方面”）是一家基于温哥华的生物技术公司，开创了新型3D生物构图技术的开发和商业化。生物打印半月板组织是Aspect技术的应用，具有临床应用的巨大潜力。该项目的目的是使用MACH-1TM机械测试系统（BioMentum，Laval，Quebec）应用机电测试协议，对生物打印的半月板移植物进行了实用的迭代。这些方案是在我们原始的启用下开发的，将确定缝合力的拉力强度，拉伸强度和Themeniscal移植物的压缩刚度。这是成功的半月板移植物发展的关键一步。