Explaining the differences in affinity and of carbohydrate binding of the glycogen-sensing enzyme, AMP-protein activated kinase (AMPK)

解释糖原感应酶、AMP 蛋白激活激酶 (AMPK) 的亲和力和碳水化合物结合的差异

• 批准号: DP110103161
• 负责人: Prof Paul Gooley
• 金额: $ 30.23万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-07-21 至 2014-07-20
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP110103161
• 关键词: Explaining; differences; affinity; carbohydrate; binding

This project will provide fundamental molecular knowledge of how a complex enzyme, AMPK is controlled by the major sugar molecule, glycogen. Our research will increase our understanding of its role in metabolic diseases such as Type 2 diabetes and obesity.

这个项目将提供一个复杂的酶，AMPK是如何由主要的糖分子，糖原控制的基本分子知识。我们的研究将增加我们对它在2型糖尿病和肥胖等代谢疾病中作用的理解。