The proprotein convertase 7 (PCSK7) regulates triglyceride levels via enhanced apolipoprotein A5 degradation

前蛋白转化酶 7 (PCSK7) 通过增强载脂蛋白 A5 降解来调节甘油三酯水平

• 批准号: 382822
• 负责人: ASHRAF yahya
• 金额: $ 0.07万
• 依托单位: Institut de recherches cliniques de Montral
• 依托单位国家: 加拿大
• 财政年份: 2018
• 资助国家: 加拿大
• 起止时间: 2018-02-01 至 2019-02-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=382822&lang=en
• 关键词: Adiposity; Apolipoprotein A5; Lipid Metabolism; Lipoproptein Lipase; Pcsk9; Proprotein Convertase 7 (Pcsk7)

Cardiovascular disease (CVD) causes one-third of deaths in Canada and represents approximately $22 billion in health care costs and lost productivity annually. One of risk factor for CVD is hypertriglyceridemia (HTG), which is the medical term for a high

心血管疾病(CVD)是加拿大三分之一的死亡原因，每年造成约220亿美元的医疗成本和生产力损失。心血管疾病的危险因素之一是高甘油三酯血症(HTG)，这是高甘油三酯的医学术语