Microfluidics for biological systems

用于生物系统的微流控

• 批准号: 1000229246-2013
• 负责人: Kumar, Aloke
• 金额: $ 0.76万
• 依托单位: University of Alberta
• 依托单位国家: 加拿大
• 项目类别: Canada Research Chairs
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=642582
• 关键词: Microfluidics; biological; systems

In natural and artificial environments, surfaces with moisture are easily colonized by bacteria, which grow into dense hydrated structures called biofiolms. Biofilms are very resistant to external stresses, which make them relevant to several aspects of human health. The proposed research program addresses this biological phenomenon through the use of microfluidic platforms, which are essentially miniaturized analytical systems. Microfluidic platforms will be used to assess utility of electric fields for preventing biofilms. These platforms will also be used to understand how biofilms form in complex habitats. The proposed program will significantly benefit areas such as human health and water filtration.

在自然和人工环境中，潮湿的表面很容易被细菌定居，细菌生长成密集的水合结构，称为生物膜。生物膜对外部压力具有很强的抵抗力，这使它们与人类健康的几个方面有关。拟议的研究计划通过使用微流控平台来解决这种生物现象，微流控平台本质上是微型分析系统。微流控平台将被用来评估电场对防止生物膜的效用。这些平台还将被用来了解生物膜如何在复杂的生境中形成。拟议的计划将极大地惠及人类健康和水过滤等领域。