Genetic variation in the cholesteryl ester transfer protein (CETP) gene influences HDL cholesterol levels and clinical outcomes in sepsis

胆固醇酯转移蛋白（CETP）基因的遗传变异影响脓毒症的高密度脂蛋白胆固醇水平和临床结果

• 批准号: 382824
• 负责人: Trinder Mark E
• 金额: $ 0.07万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 财政年份: 2018
• 资助国家: 加拿大
• 起止时间: 2018-02-01 至 2019-02-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=382824&lang=en
• 关键词: Cholesterol; Cholesteryl Ester Transfer Protein; Genetics; High-Density Lipoprotein; Lipids; Lipoprotein; Metabolism; Next-Generation Sequencing; Sepsis

Sepsis is one of the leading causes of death of Canadians. Sepsis occurs when the immune system is activated by microbes during a severe infection. "Good" cholesterol known as high-density lipoprotein can act like a mop to clean up the toxins produced by

败血症是加拿大人死亡的主要原因之一。脓毒症发生时，免疫系统是由微生物在严重感染激活。“好”胆固醇，即高密度脂蛋白，可以像拖把一样清理体内产生的毒素。