Bioanalytical Chemistry and Biointerfaces

生物分析化学和生物界面

• 批准号: 1000227325-2011
• 负责人: Brennan, John
• 金额: $ 14.57万
• 依托单位: McMaster University
• 依托单位国家: 加拿大
• 项目类别: Canada Research Chairs
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=642916
• 关键词: Bioanalytical; Chemistry; Biointerfaces

The development of new materials which can interact with biological systems in a desired way is vital to many established and emerging industrial sectors, including diagnostics, drug discovery and implantable devices. Dr. Brennan will use infrastructure within the newly established Biointerfaces Institute to create a novel, high-throughput approach to discovery and characterization of new biomaterials and surfaces. Much of this work will focus on developing new materials for the immobilization of biomolecules, the development of improved analytical devices based on such materials, and applying the devices for environmental and health monitoring. This work has the potential to spin out new commercial products and new companies, to lead to improved point-of-care diagnostic devices, and to revolutionize drug-screening technologies.

能够以所需方式与生物系统相互作用的新材料的开发对于许多已建立和新兴的工业部门至关重要，包括诊断，药物发现和植入式设备。Brennan博士将利用新成立的生物界面研究所的基础设施，创建一种新的高通量方法来发现和表征新的生物材料和表面。 这项工作的大部分将集中在开发用于固定生物分子的新材料，开发基于此类材料的改进分析设备，并将设备应用于环境和健康监测。 这项工作有可能产生新的商业产品和新的公司，导致改进的床旁诊断设备，并彻底改变药物筛选技术。