Point-of-Care Diagnostics

即时诊断

• 批准号: CRC-2018-00047
• 负责人: Brennan, John
• 金额: $ 14.57万
• 依托单位: McMaster University
• 依托单位国家: 加拿大
• 项目类别: Canada Research Chairs
• 财政年份: 2020
• 资助国家: 加拿大
• 起止时间: 2020-01-01 至 2021-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=695704
• 关键词: Point; Care; Diagnostics

My research program will focus on the discovery, development and translation of new point-of-care assays and diagnostic devices using high-throughput approaches and common platform chemistries to allow for more rapid discovery, optimization, translation and commercialization of transformative diagnostic technologies. Our approach will integrate functional DNA superstructures (based on rolling circle amplification of aptamers and DNA enzymes), high throughput assay development and optimization methods, and advanced printing technologies to create new diagnostic devices that can be easily manufactured and translated to industry partners. These advanced diagnostic devices will improve clinical practice, reduce healthcare costs and improve quality of care.

我的研究项目将专注于使用高通量方法和通用平台化学的新护理点检测和诊断设备的发现、开发和翻译，以允许更快地发现、优化、翻译和商业化变革性诊断技术。我们的方法将整合功能性DNA超结构（基于核酸适体和DNA酶的滚圈扩增），高通量分析开发和优化方法，以及先进的打印技术，以创建新的诊断设备，可以很容易地制造和翻译给行业合作伙伴。这些先进的诊断设备将改善临床实践，降低医疗成本，提高护理质量。