Harnessing the power of Monocytes/Macrophages in Intestinal Immunity to Candidiasis

利用单核细胞/巨噬细胞的肠道免疫能力对抗念珠菌病

• 批准号: 388137
• 负责人: Vinh Donald C
• 金额: $ 49.6万
• 依托单位: Research Institute of the McGill University Health Centre
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2018
• 资助国家: 加拿大
• 起止时间: 2018-09-01 至 2023-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=388137&lang=en
• 关键词: Card9; Gm-Csf; Innate Immunity; Invasive Candidiasis; Macrophage; Monocyte

Invasive fungal infections affect more than 2 million people worldwide annually, and result in death for more than half of these patients. In a healthy immune system, a hormone called GM-CSF activates antifungal defenses to protect against fungal infectio

侵袭性真菌感染每年影响全球超过200万人，并导致这些患者中一半以上死亡。在健康的免疫系统中，一种称为GM-CSF的激素激活抗真菌防御，以防止真菌感染。