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Structural analysis of mycobacterial oxidative phosphorylation and targeting it to treat tuberculosis

Structural analysis of mycobacterial oxidative phosphorylation and targeting it to treat tuberculosis
分枝杆菌氧化磷酸化的结构分析及其靶向治疗结核病
批准号:
387707
负责人:
Rubinstein John L
金额:
$69.38万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2018
资助国家:
加拿大
项目状态:
已结题
起止时间:
2018-09-01 至 2023-09-01

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中文摘要
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英文摘要
Cells use oxygen to convert chemical energy from diverse sources into the universal energy currency ATP before use. This process, called oxidative phosphorylation (OxPhos), is performed by a series of large molecular machines that reside in cell membranes
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Understanding mycobacterial oxidative phosphorylation and targeting it to treat tuberculosis
  • 批准号:
    487542
  • 项目类别:
    Operating Grants
  • 资助金额:
    $86.94万
  • 财政年份:
    2023
  • 负责人:
    Rubinstein John L
  • 依托单位:
Canada Research Chair - Tier 1
  • 批准号:
    453863
  • 项目类别:
  • 资助金额:
    $101.99万
  • 财政年份:
    2020
  • 负责人:
    Rubinstein John L
  • 依托单位:
Electron cryomicroscopy studies of eukaryotic rotary ATPases
  • 批准号:
    400606
  • 项目类别:
    Operating Grants
  • 资助金额:
    $69.38万
  • 财政年份:
    2019
  • 负责人:
    Rubinstein John L
  • 依托单位:
Cryo-EM analysis of the structure and dynamics of protein assemblies at energized membranes
  • 批准号:
    387628
  • 项目类别:
    Operating Grants
  • 资助金额:
    $152.07万
  • 财政年份:
    2018
  • 负责人:
    Rubinstein John L
  • 依托单位:
海外基金