Development of Hierarchical Micro/Nano Structured Multi-Responsive Surfaces for Microfluid Applications
用于微流体应用的分层微/纳米结构多响应表面的开发
基本信息
- 批准号:RGPIN-2016-06766
- 负责人:
- 金额:$ 3.13万
- 依托单位:
- 依托单位国家:加拿大
- 项目类别:Discovery Grants Program - Individual
- 财政年份:2018
- 资助国家:加拿大
- 起止时间:2018-01-01 至 2019-12-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Recent advances in stimuli-responsive coatings enable their integration as functional elements in nanotechnologies such as microfluidics, Micro Electro-Mechanical Systems (MEMS) where interfacial forces strongly influence the device performance because of the large surface-to-volume ratio. However, responsive coatings are suffering from major shortcomings: (i) lack of responsiveness rapidity, selectivity and reversibility, (ii) poor environmental stability, (iii) limited understanding of the structure–function relationship, which are all critical to design reliable rules for building multifunctional surfaces. Using approaches from surface chemistry, polymer sciences and self-assembly, the proposed program aims to overcome these limitations by developing and investigating a new generation of responsive hierarchical micro/nano-structured coatings whose physical properties (structure and mechanical properties) and surface chemistry can be tuned independently and reversibly using different external stimuli (light, temperature, pH, ionic strength). ***The proposed microstructure consists of 2D nanogel arrays permanently attached to substrates and whose size and elasticity (via swelling/shrinking behavior) can be modulated by temperature or light allowing surface topography (roughness) and stiffness to be reversibly controlled. The nanogel surface will be functionalized with polymer brushes whose nanostructure and chemistry can be independently controlled using different stimuli (pH, ionic strength or temperature) depending on the desired adaptive fine surface properties. The microstructure is expected to enhance the effect of surface chemistry of the outer brush layer. The program will involve four aspects: (i) development and optimization of thermo-responsive 2D nanogel arrays functionalized with different polymer brushes, (ii) development and optimization of photo-responsive nanogels exhibiting significant swelling effects and their immobilization into 2D arrays, (iii) investigation and optimization of the responsive behavior of the coatings developed in (i) and (ii) towards different stimuli and (iv) exploration of potential applications as functional elements for fluid control in microfluidics.***The various ways the proposed hierarchical nano/micro structures can be modulated will most likely enable revolutionary advances and creation of new technologies, particularly in biomedical surface engineering and microfluidics where advanced assembly of small functional components are increasingly required.*****
刺激响应涂层的最新进展使它们能够作为功能元件集成在纳米技术中,例如微流体、微机电系统(MEMS),其中由于大的表面积与体积比,界面力强烈影响器件性能。然而,响应性涂料的主要缺点是:(i)缺乏响应速度,选择性和可逆性,(ii)环境稳定性差,(iii)对结构-功能关系的理解有限,这些都是设计用于构建多功能表面的可靠规则的关键。利用表面化学,聚合物科学和自组装的方法,拟议的计划旨在通过开发和研究新一代响应分层微/纳米结构涂层来克服这些限制,这些涂层的物理特性(结构和机械特性)和表面化学可以使用不同的外部刺激(光,温度,pH值,离子强度)独立和可逆地进行调整。* 所提出的微结构由永久附着于基底的2D纳米凝胶阵列组成,其尺寸和弹性(通过溶胀/收缩行为)可以通过温度或光进行调节,从而可逆地控制表面形貌(粗糙度)和刚度。纳米凝胶表面将用聚合物刷官能化,聚合物刷的纳米结构和化学性质可以根据所需的自适应精细表面性质使用不同的刺激(pH、离子强度或温度)独立控制。该微结构有望增强外刷层的表面化学效果。该计划将涉及四个方面:(i)开发和优化用不同聚合物刷官能化的热响应2D纳米凝胶阵列,(ii)开发和优化表现出显著溶胀效应的光响应纳米凝胶及其固定到2D阵列中,(iii)研究和优化在(i)和(ii)中开发的涂层对不同刺激的响应行为,以及(iv)探索作为微流体中流体控制的功能元件的潜在应用。所提出的分级纳米/微米结构可以被调制的各种方式将最有可能实现革命性的进步和新技术的创造,特别是在生物医学表面工程和微流体领域,其中越来越需要小型功能组件的先进组装。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Giasson, Suzanne其他文献
Long-circulating poly(ethylene glycol)-coated emulsions to target solid tumors
- DOI:
10.1016/j.ejpb.2007.03.016 - 发表时间:
2007-09-01 - 期刊:
- 影响因子:4.9
- 作者:
Rossi, Joanna;Giasson, Suzanne;Leroux, Jean-Christophe - 通讯作者:
Leroux, Jean-Christophe
Normal and frictional forces between surfaces bearing polyelectrolyte brushes
- DOI:
10.1021/la7039724 - 发表时间:
2008-08-19 - 期刊:
- 影响因子:3.9
- 作者:
Raviv, Uri;Giasson, Suzanne;Klein, Jacob - 通讯作者:
Klein, Jacob
Amino-functionalized monolayers covalently grafted to silica-based substrates as a robust primer anchorage in aqueous media
- DOI:
10.1016/j.apsusc.2016.02.141 - 发表时间:
2016-05-01 - 期刊:
- 影响因子:6.7
- 作者:
Giraud, Lucie;Nadarajah, Rakini;Giasson, Suzanne - 通讯作者:
Giasson, Suzanne
Stability of silanols and grafted alkylsilane monolayers on plasma-activated mica surfaces
- DOI:
10.1021/la703522u - 发表时间:
2008-04-01 - 期刊:
- 影响因子:3.9
- 作者:
Liberelle, Benoit;Banquy, Xavier;Giasson, Suzanne - 通讯作者:
Giasson, Suzanne
Friction and normal interaction forces between irreversibly attached weakly charged polymer brushes
- DOI:
10.1021/la702367f - 发表时间:
2008-02-19 - 期刊:
- 影响因子:3.9
- 作者:
Liberelle, Benoit;Giasson, Suzanne - 通讯作者:
Giasson, Suzanne
Giasson, Suzanne的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Giasson, Suzanne', 18)}}的其他基金
Development of Hierarchical Micro/Nano Structured Multi-Responsive Surfaces for Microfluid Applications
用于微流体应用的分层微/纳米结构多响应表面的开发
- 批准号:
RGPIN-2016-06766 - 财政年份:2021
- 资助金额:
$ 3.13万 - 项目类别:
Discovery Grants Program - Individual
Development of Hierarchical Micro/Nano Structured Multi-Responsive Surfaces for Microfluid Applications
用于微流体应用的分层微/纳米结构多响应表面的开发
- 批准号:
RGPIN-2016-06766 - 财政年份:2020
- 资助金额:
$ 3.13万 - 项目类别:
Discovery Grants Program - Individual
Development of Hierarchical Micro/Nano Structured Multi-Responsive Surfaces for Microfluid Applications
用于微流体应用的分层微/纳米结构多响应表面的开发
- 批准号:
RGPIN-2016-06766 - 财政年份:2019
- 资助金额:
$ 3.13万 - 项目类别:
Discovery Grants Program - Individual
Development of Hierarchical Micro/Nano Structured Multi-Responsive Surfaces for Microfluid Applications
用于微流体应用的分层微/纳米结构多响应表面的开发
- 批准号:
RGPIN-2016-06766 - 财政年份:2017
- 资助金额:
$ 3.13万 - 项目类别:
Discovery Grants Program - Individual
Stimuli-responsive hierarchical roughness providing superhydrophobicity in a surfactant rich environment
刺激响应分级粗糙度在富含表面活性剂的环境中提供超疏水性
- 批准号:
486784-2015 - 财政年份:2015
- 资助金额:
$ 3.13万 - 项目类别:
Engage Grants Program
Towards the control of surface properties via nanostructured polymeric materials
通过纳米结构聚合物材料控制表面性能
- 批准号:
184222-2010 - 财政年份:2015
- 资助金额:
$ 3.13万 - 项目类别:
Discovery Grants Program - Individual
Towards the control of surface properties via nanostructured polymeric materials
通过纳米结构聚合物材料控制表面性能
- 批准号:
184222-2010 - 财政年份:2014
- 资助金额:
$ 3.13万 - 项目类别:
Discovery Grants Program - Individual
Towards the control of surface properties via nanostructured polymeric materials
通过纳米结构聚合物材料控制表面性能
- 批准号:
184222-2010 - 财政年份:2013
- 资助金额:
$ 3.13万 - 项目类别:
Discovery Grants Program - Individual
Towards the control of surface properties via nanostructured polymeric materials
通过纳米结构聚合物材料控制表面性能
- 批准号:
184222-2010 - 财政年份:2012
- 资助金额:
$ 3.13万 - 项目类别:
Discovery Grants Program - Individual
Towards the control of surface properties via nanostructured polymeric materials
通过纳米结构聚合物材料控制表面性能
- 批准号:
184222-2010 - 财政年份:2011
- 资助金额:
$ 3.13万 - 项目类别:
Discovery Grants Program - Individual
相似国自然基金
丙烷脱氢Pt@hierarchical zeolite催化剂的设计制备与反应调控
- 批准号:22178062
- 批准年份:2021
- 资助金额:60 万元
- 项目类别:面上项目
相似海外基金
Development of Hierarchical Micro/Nano Structured Multi-Responsive Surfaces for Microfluid Applications
用于微流体应用的分层微/纳米结构多响应表面的开发
- 批准号:
RGPIN-2016-06766 - 财政年份:2021
- 资助金额:
$ 3.13万 - 项目类别:
Discovery Grants Program - Individual
Development of Hierarchical Micro/Nano Structured Multi-Responsive Surfaces for Microfluid Applications
用于微流体应用的分层微/纳米结构多响应表面的开发
- 批准号:
RGPIN-2016-06766 - 财政年份:2020
- 资助金额:
$ 3.13万 - 项目类别:
Discovery Grants Program - Individual
Development of Hierarchical Micro/Nano Structured Multi-Responsive Surfaces for Microfluid Applications
用于微流体应用的分层微/纳米结构多响应表面的开发
- 批准号:
RGPIN-2016-06766 - 财政年份:2019
- 资助金额:
$ 3.13万 - 项目类别:
Discovery Grants Program - Individual
Hierarchical 3D micro/nanostructured LiMn1-xFexPO4/graphene hybrid composite for high power Li-ion battery and its dynamic study by in-situ X-ray absorption and THz spectroscopies
用于高功率锂离子电池的分层3D微/纳米结构LiMn1-xFexPO4/石墨烯杂化复合材料及其原位X射线吸收和太赫兹光谱动态研究
- 批准号:
494159-2016 - 财政年份:2018
- 资助金额:
$ 3.13万 - 项目类别:
Strategic Projects - Group
Development of Hierarchical Micro/Nano Structured Multi-Responsive Surfaces for Microfluid Applications
用于微流体应用的分层微/纳米结构多响应表面的开发
- 批准号:
RGPIN-2016-06766 - 财政年份:2017
- 资助金额:
$ 3.13万 - 项目类别:
Discovery Grants Program - Individual
Hierarchical 3D micro/nanostructured LiMn1-xFexPO4/graphene hybrid composite for high power Li-ion battery and its dynamic study by in-situ X-ray absorption and THz spectroscopies
用于高功率锂离子电池的分层3D微/纳米结构LiMn1-xFexPO4/石墨烯杂化复合材料及其原位X射线吸收和太赫兹光谱动态研究
- 批准号:
494159-2016 - 财政年份:2017
- 资助金额:
$ 3.13万 - 项目类别:
Strategic Projects - Group
Hierarchical 3D micro/nanostructured LiMn1-xFexPO4/graphene hybrid composite for high power Li-ion battery and its dynamic study by in-situ X-ray absorption and THz spectroscopies
用于高功率锂离子电池的分层3D微/纳米结构LiMn1-xFexPO4/石墨烯杂化复合材料及其原位X射线吸收和太赫兹光谱动态研究
- 批准号:
494159-2016 - 财政年份:2016
- 资助金额:
$ 3.13万 - 项目类别:
Strategic Projects - Group
Osteoderms of Heloderma suspectum - A new nano-micro hierarchical biomineralized structure in vertebrates
疑似蛇皮的骨皮——脊椎动物中一种新的纳米-微米分层生物矿化结构
- 批准号:
1789616 - 财政年份:2016
- 资助金额:
$ 3.13万 - 项目类别:
Studentship
Development of a novel bioorganic electronic device mimicking a micro-hierarchical structure in the intestinal tract for a miniature electrical power source
开发一种模仿肠道微层次结构的新型生物有机电子器件,用于微型电源
- 批准号:
16K18257 - 财政年份:2016
- 资助金额:
$ 3.13万 - 项目类别:
Grant-in-Aid for Young Scientists (B)
EAGER: Experimental Investigation of Forced Convection on Hierarchical Micro/Nanoporous Conducting-Lubricating Surfaces
EAGER:分级微/纳米多孔导电润滑表面强制对流的实验研究
- 批准号:
1449621 - 财政年份:2014
- 资助金额:
$ 3.13万 - 项目类别:
Standard Grant