Development of Characterization Controls for 3D-Printed Implants by Direct Energy Deposition

通过直接能量沉积开发 3D 打印植入物的表征控制

基本信息

  • 批准号:
    523141-2018
  • 负责人:
  • 金额:
    $ 1.82万
  • 依托单位:
  • 依托单位国家:
    加拿大
  • 项目类别:
    Engage Grants Program
  • 财政年份:
    2018
  • 资助国家:
    加拿大
  • 起止时间:
    2018-01-01 至 2019-12-31
  • 项目状态:
    已结题

项目摘要

Currently, the largest market share of biomedical implants consists of devices fabricated from metallic materials such as titanium,**and cobalt-chromium alloys using conventional casting processes. While the implantation of these metallic biomaterials has**become common place in dentistry, oral maxillofacial, and joint replacement surgeries, between 10-15% of orthopaedic and 2% of**dental implants still fail in service. The lack of patient specific devices with both appropriate mechanical, materials and biological**properties is one of the causes for this failure. With instruments now capable of printing metals, additive manufacturing, or 3Dprinting,**is a promising technology for manufacturing customized medical implant devices that can be optimized for better success.**However, there remains several challenges related to the materials optimization during additive manufacturing to meet the**stringent materials and mechanical properties for medical implant regulations. A thorough and robust high-resolution materials**characterization and understanding of local mechanical properties will help to advance biomedical implants produced by additive**manufacturing. Liburdi Engineering is interested in developing their manufacturing instrumentation for applications in additive**manufacturing of biomedical implants, since their current direct energy deposition technology has several advantages to**conventional powder-bed additive manufacturing. By partnering with McMaster University, this project will provide significant**advancements in developing the 3D-printing technology by understanding and optimizing the materials produced.**.**Ontario
目前,生物医学植入物的最大市场份额由使用传统铸造工艺的钛、**和钴铬合金等金属材料制成的装置组成。虽然这些金属生物材料的植入已经成为牙科、口腔颌面和关节置换手术中的常见领域,但10%-15%的矫形外科和2%的牙科植入物仍然无法使用。缺乏具有适当的机械、材料和生物**特性的患者专用设备是导致这一失败的原因之一。随着仪器现在能够打印金属、添加剂制造或3D打印,**是一种很有前途的制造定制医疗植入物设备的技术,可以优化以获得更好的成功。**然而,在添加剂制造过程中,仍存在与材料优化相关的几个挑战,以满足**严格的医疗植入物材料和机械性能法规。彻底和强大的高分辨率材料**表征和了解当地的机械性能将有助于推动通过添加**制造生产的生物医学植入物。Liburdi Engineering有兴趣开发他们的制造仪器,用于生物医学植入物的添加剂制造**,因为他们目前的直接能量沉积技术与**传统的粉床添加剂制造相比具有几个优势。通过与麦克马斯特大学的合作,该项目将通过了解和优化生产的材料,在开发3D打印技术方面取得重大进步。**。**安大略省

项目成果

期刊论文数量(0)
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专利数量(0)

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Grandfield, Kathryn其他文献

Fabrication of polycaprolactone electrospun nanofibers doped with silver nanoparticles formed by air plasma treatment
  • DOI:
    10.1088/1361-6528/ab0444
  • 发表时间:
    2019-05-24
  • 期刊:
  • 影响因子:
    3.5
  • 作者:
    Binkley, Dakota M.;Le, Bryan E. J.;Grandfield, Kathryn
  • 通讯作者:
    Grandfield, Kathryn
Ultrastructure of Bone: Hierarchical Features from Nanometer to Micrometer Scale Revealed in Focused Ion Beam Sections in the TEM
  • DOI:
    10.1007/s00223-018-0454-9
  • 发表时间:
    2018-12-01
  • 期刊:
  • 影响因子:
    4.2
  • 作者:
    Grandfield, Kathryn;Vuong, Vicky;Schwarcz, Henry P.
  • 通讯作者:
    Schwarcz, Henry P.
Bone Response to Free-Form Fabricated Hydroxyapatite and Zirconia Scaffolds: A Transmission Electron Microscopy Study in the Human Maxilla
Selective Voronoi tessellation as a method to design anisotropic and biomimetic implants
Multimodal and Multiscale Characterization of the Bone-Bacteria Interface in a Case of Medication-Related Osteonecrosis of the Jaw.
  • DOI:
    10.1002/jbm4.10693
  • 发表时间:
    2022-12
  • 期刊:
  • 影响因子:
    3.8
  • 作者:
    Micheletti, Chiara;DiCecco, Liza-Anastasia;Wexell, Cecilia Larsson;Binkley, Dakota M.;Palmquist, Anders;Grandfield, Kathryn;Shah, Furqan A.
  • 通讯作者:
    Shah, Furqan A.

Grandfield, Kathryn的其他文献

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{{ truncateString('Grandfield, Kathryn', 18)}}的其他基金

Microscopy of Biomaterials and Biointerfaces
生物材料和生物界面的显微镜
  • 批准号:
    CRC-2020-00191
  • 财政年份:
    2022
  • 资助金额:
    $ 1.82万
  • 项目类别:
    Canada Research Chairs
Atom-by-atom, multispectral, and real-time characterization for osseous applications
骨应用的逐原子、多光谱和实时表征
  • 批准号:
    RGPIN-2020-05722
  • 财政年份:
    2022
  • 资助金额:
    $ 1.82万
  • 项目类别:
    Discovery Grants Program - Individual
Atom-by-atom, multispectral, and real-time characterization for osseous applications
骨应用的逐原子、多光谱和实时表征
  • 批准号:
    RGPIN-2020-05722
  • 财政年份:
    2021
  • 资助金额:
    $ 1.82万
  • 项目类别:
    Discovery Grants Program - Individual
Microscopy Of Biomaterials And Biointerfaces
生物材料和生物界面的显微镜
  • 批准号:
    CRC-2020-00191
  • 财政年份:
    2021
  • 资助金额:
    $ 1.82万
  • 项目类别:
    Canada Research Chairs
Atom-by-atom, multispectral, and real-time characterization for osseous applications
骨应用的逐原子、多光谱和实时表征
  • 批准号:
    RGPIN-2020-05722
  • 财政年份:
    2020
  • 资助金额:
    $ 1.82万
  • 项目类别:
    Discovery Grants Program - Individual
Microscopy of Biomaterials and Biointerfaces
生物材料和生物界面的显微镜
  • 批准号:
    1000233075-2019
  • 财政年份:
    2020
  • 资助金额:
    $ 1.82万
  • 项目类别:
    Canada Research Chairs
Development and High Resolution Characterization of Bone-Interfacing Biomaterials
骨界面生物材料的开发和高分辨率表征
  • 批准号:
    RGPIN-2014-06053
  • 财政年份:
    2019
  • 资助金额:
    $ 1.82万
  • 项目类别:
    Discovery Grants Program - Individual
Development and High Resolution Characterization of Bone-Interfacing Biomaterials
骨界面生物材料的开发和高分辨率表征
  • 批准号:
    RGPIN-2014-06053
  • 财政年份:
    2018
  • 资助金额:
    $ 1.82万
  • 项目类别:
    Discovery Grants Program - Individual
Development and High Resolution Characterization of Bone-Interfacing Biomaterials
骨界面生物材料的开发和高分辨率表征
  • 批准号:
    RGPIN-2014-06053
  • 财政年份:
    2017
  • 资助金额:
    $ 1.82万
  • 项目类别:
    Discovery Grants Program - Individual
Liquid Heating Holder for Transmission Electron Microscope
透射电子显微镜液体加热支架
  • 批准号:
    RTI-2017-00267
  • 财政年份:
    2016
  • 资助金额:
    $ 1.82万
  • 项目类别:
    Research Tools and Instruments

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