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Identifying co-operating genetic mutations within large chromosomal deletions associated with triple negative breast cancer

Identifying co-operating genetic mutations within large chromosomal deletions associated with triple negative breast cancer
识别与三阴性乳腺癌相关的大染色体缺失中的协同基因突变
批准号：
392451
负责人：
Kuzmin Elena
金额：
$10.2万
依托单位：
McGill University
依托单位国家：
加拿大
项目类别：
Fellowship Programs
财政年份：
2018
资助国家：
加拿大
项目状态：
已结题
起止时间：
2018-09-01 至 2020-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=392451&lang=en
关键词：
Breast Cancer Cancer Genetics Copy Number Aberration Crispr-Cas9 Functional Genomics Genetic Networks Large Chromosomal Deletions

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中文摘要
翻译
癌症与基因突变的积累有关，这些基因改变赋予癌细胞失控生长的能力。这些改变可能导致正常调节细胞g的基因的有害功能增加或功能丧失。
英文摘要
Cancer is associated with an accumulation of alterations in genes that confer the ability of cancer cells to grow uncontrollably. These alterations can contribute to increased deleterious function or loss of function of genes that normally regulate cell g
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会议论文
Mapping genetic networks of large copy number variants in cancer
Canada Research Chair - Tier 2
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