Canada 150 Research Chair in Evolutionary Genomics

加拿大 150 进化基因组学研究主席

• 批准号: 10009000037-2018
• 负责人: Mank, JudithElizabeth
• 金额: $ 54.64万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Canada 150 Research Chairs
• 财政年份: 2018
• 资助国家: 加拿大
• 起止时间: 2018-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=654907
• 关键词: Canada; 150; Research; Chair; Evolutionary

Prof. Mank studies the genetic basis and evolutionary causes of sexual dimorphism, arguably the most pervasive form of intra-specific diversity in the animal kingdom. Males and females in many animals differ for a broad array of traits, including morphology, physiology and behaviour. Her cutting-edge research programme combines population genomic and transcriptomic approaches with functional genetics to reveal the genetic causes and evolutionary consequences of sexual dimorphism. Additionally, sex differences in disease incidence and therapeutic response have recently emerged as major biomedical concerns, and she works with biomedics to understand the genetic basis of sexual dimorphism in clinically relevant contexts.

Mank教授研究了性二型的遗传基础和进化原因，可以说是动物王国中种内多样性最普遍的形式。许多动物的雄性和雌性在一系列广泛的特征上存在差异，包括形态学，生理学和行为。她的前沿研究计划将人口基因组学和转录组学方法与功能遗传学相结合，以揭示性二态性的遗传原因和进化后果。此外，疾病发病率和治疗反应的性别差异最近已成为主要的生物医学问题，她与生物医学合作，以了解临床相关背景下性二态性的遗传基础。