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Identifying and characterizing pathogen-associated, conserved hypothetical proteins with potential novel roles in virulence, from over 8000 bacterial genomes

Identifying and characterizing pathogen-associated, conserved hypothetical proteins with potential novel roles in virulence, from over 8000 bacterial genomes
从 8000 多个细菌基因组中识别和表征与病原体相关的保守假设蛋白质，这些蛋白质在毒力方面具有潜在的新作用
批准号：
408167
负责人：
Lau Wing Yin Venus
金额：
$7.65万
依托单位：
Simon Fraser University (Burnaby, B.C.)
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2018
资助国家：
加拿大
项目状态：
已结题
起止时间：
2018-10-01 至 2021-10-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=408167&lang=en
关键词：
Anti-Infective Big Data Bioinformatics Comparative Genomics Conserved Hypothetical Proteins Genomic Epidemiology Microbial Genomics Virulence Mechanisms

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The vast expansion of DNA data now enables large-scale comparisons of thousands of bacterial genomes to elucidate the distinction in gene/protein composition between pathogens (disease-causing microbes) and non-pathogens. Proteins found exclusively in pat
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Scalable Learning and Optimization: High-dimensional Models and Online Decision-Making Strategies for Big Data Analysis