Identifying and characterizing pathogen-associated, conserved hypothetical proteins with potential novel roles in virulence, from over 8000 bacterial genomes

从 8000 多个细菌基因组中识别和表征与病原体相关的保守假设蛋白质，这些蛋白质在毒力方面具有潜在的新作用

• 批准号: 408167
• 负责人: Lau Wing Yin Venus
• 金额: $ 7.65万
• 依托单位: Simon Fraser University (Burnaby, B.C.)
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2018
• 资助国家: 加拿大
• 起止时间: 2018-10-01 至 2021-10-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=408167&lang=en
• 关键词: Anti-Infective; Big Data; Bioinformatics; Comparative Genomics; Conserved Hypothetical Proteins; Genomic Epidemiology; Microbial Genomics; Virulence Mechanisms

The vast expansion of DNA data now enables large-scale comparisons of thousands of bacterial genomes to elucidate the distinction in gene/protein composition between pathogens (disease-causing microbes) and non-pathogens. Proteins found exclusively in pat

DNA数据的巨大扩展现在能够对数千个细菌基因组进行大规模比较，以阐明病原体(致病微生物)和非病原体在基因/蛋白质组成上的区别。仅在PAT中发现的蛋白质