Bioinformatics and big data analytics

生物信息学和大数据分析

• 批准号: CRC-2016-00137
• 负责人: Xia, Jianguo
• 金额: $ 8.74万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Canada Research Chairs
• 财政年份: 2020
• 资助国家: 加拿大
• 起止时间: 2020-01-01 至 2021-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=696003
• 关键词: Bioinformatics; big; data; analytics

Food, gut microbes and environmental chemicals all have strong impacts on animal health through complex biochemical reactions and metabolic processes. Understanding the underlying molecular mechanisms holds great promise to significantly improve public health, food and environmental safety. The objectives of my research program are i) developing novel computational algorithms to enable high-throughput metabolic profiling; ii) employing big data analytics to elucidate molecular targets for environmental chemicals; and iii) validations and translational applications to ecosystem and population studies.

食物、肠道微生物和环境化学物质都通过复杂的生化反应和代谢过程对动物健康产生强烈影响。了解潜在的分子机制对显着改善公共卫生，食品和环境安全具有很大的希望。我的研究计划的目标是：i）开发新的计算算法，以实现高通量代谢分析; ii）采用大数据分析来阐明环境化学品的分子目标; iii）验证和转化应用于生态系统和人口研究。