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Investigating the lymphocyte-activation gene 3 (LAG-3) exhaustion marker and its associated defects in invariant Natural Killer T (iNKT) immune cell function in HIV infection

Investigating the lymphocyte-activation gene 3 (LAG-3) exhaustion marker and its associated defects in invariant Natural Killer T (iNKT) immune cell function in HIV infection
研究 HIV 感染中淋巴细胞激活基因 3 (LAG-3) 耗竭标记及其与不变自然杀伤 T (iNKT) 免疫细胞功能相关的缺陷
批准号:
396595
负责人:
Balasko Allison
金额:
$10.93万
依托单位:
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2018
资助国家:
加拿大
项目状态:
已结题
起止时间:
2018-10-01 至 2021-10-01

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中文摘要
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英文摘要
Background: Human immunodeficiency virus (HIV) is a global health issue, with 36.9 million HIV-infected people in 2018. HIV exhausts the infected person's immune system to the point where it cannot properly fight infections. Despite treatment with anti-HI
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Immunotherapeutic blockades targeting LAG-3 and PD-1 immune checkpoint inhibitors on invariant Natural Killer T cells: Implications in chronic HIV infection
  • 批准号:
    466216
  • 项目类别:
  • 资助金额:
    $0.18万
  • 财政年份:
    2022
  • 负责人:
    Balasko Allison
  • 依托单位:
Medical Microbiology Masters Student
  • 批准号:
    367032
  • 项目类别:
    Studentship Programs
  • 资助金额:
    $1.27万
  • 财政年份:
    2016
  • 负责人:
    Balasko Allison
  • 依托单位:
海外基金