Investigating the role of cellular metabolism in effector T cell responses and T cell exhaustion

研究细胞代谢在效应 T 细胞反应和 T 细胞耗竭中的作用

• 批准号: 397460
• 负责人: Roy Dominic
• 金额: $ 9.83万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Fellowship Programs
• 财政年份: 2018
• 资助国家: 加拿大
• 起止时间: 2018-11-01 至 2021-11-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=397460&lang=en
• 关键词: Cancer; Immunity; Infection; Metabolism; T Cell Exhaustion; T Cells

T cells play a crucial role in the immune response against infections and cancer. Over the course of an immune response, T cells engage various metabolic pathways to meet the energetic demands of expansion and development of their effector functions. The

T细胞在对抗感染和癌症的免疫反应中起着至关重要的作用。在免疫应答的过程中，T细胞参与各种代谢途径，以满足其效应器功能扩展和发展的能量需求。的