Advanced Electronic Microsystems for Biomedical and Oilfield Instrumentation Applications

用于生物医学和油田仪表应用的先进电子微系统

• 批准号: RGPIN-2018-03701
• 负责人: Mintchev, Martin
• 金额: $ 2.04万
• 依托单位: University of Calgary
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2018
• 资助国家: 加拿大
• 起止时间: 2018-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=659850
• 关键词: Advanced; Electronic; Microsystems; Biomedical; Oilfield

The goals of my proposed research program are (a) to investigate, design, implement, and test innovative electronic microsystems for biomedical and oilfield applications; (b) develop intellectual property around them; and (c) commercialize them as soon as possible. My plan in the next 5 years is to research, develop and test two such microsystems, the In Situ Lab Aid (ISLA), a new "smart sole" device for painless, single-use blood extraction and analysis for breast cancer screening; and a miniaturized, self-calibrating, mobile inertial microsystem for downhole navigation and wireless communication in lateral drilling deviations from unproductive oil wells. The idea behind ISLA is innovative, but also realistic: after a blood sample is extracted with the combined aid of a MEMS actuator and casual walking, it is subjected to immediate interrogation in situ by a miniature high-intensity superluminescent light emitting diode and the resulting fluorescence is recorded. The hypothesis is that these fluorescence data will be extremely useful for the early diagnosis of breast cancer. A recent (2015) study on blood fluorescence spectroscopy for breast cancer screening revealed the sensitivity and specificity of this approach to be 80.4% and 100%, respectively. Having a minimally-invasive, "smart sole" device to perform blood fluorescence testing in situ will benefit immensely Canadian women in self-controlled, autonomous early breast cancer screening. The project has three components: (a) scientific (modeling the combined action of the actuator and casual walking on skin penetration in various areas of the foot, along with estimation of blood volume collection); (b) development ("smart sole" prototype design and optimization); and (c) laboratory and human testing. In the area of inertial navigation systems (INS) for downhole oil exploration, my idea is to apply the newly developed by my research group In-Drilling Allignment (IDA) technique for lateral drilling deviations from existing unproductive wells, while providing complete three-dimensional (3D) controlled motion of the INS capsule for maximal error compensation in all three planes of the drill bit motion inside these deviations. The goal is to miniaturize the IDA setup to fit in a 12x100 mm enclosure, in which a miniature electric motor will provide controlled 3D motion for error compensation. Relay-based wireless communication is also envisioned. This project has three components as well: (a) scientific (model and quantify the impact of 3D controlled motion on navigation error reduction in each of the three navigation planes and find wireless means to relay the information); (b) development (prototype design and optimization); and (c) laboratory and well-based testing. The project will benefit both the Canadian oil industry and the environment, since old unproductive oil wells will become reusable, avoiding new well drilling.

我提议的研究计划的目标是(A)调查、设计、实施和测试用于生物医学和油田应用的创新电子微系统；(B)开发围绕它们的知识产权；以及(C)尽快将它们商业化。我在未来5年的计划是研究、开发和测试两个这样的微系统，一个是原位实验室辅助(ISLA)，这是一种新的用于无痛、一次性提取血液和分析乳腺癌的“智能鞋底”设备；另一个是微型、自我校准、移动的惯性微系统，用于在非生产油井的侧向钻井偏差中进行井下导航和无线通信。Isla背后的想法是创新的，但也是现实的：在MEMS致动器和随意行走的组合帮助下提取血液样本后，它将通过微型高强度超辐射发光二极管进行即时就地询问，并记录产生的荧光。假设是这些荧光数据将对乳腺癌的早期诊断非常有用。最近(2015)的一项用于乳腺癌筛查的血液荧光光谱研究表明，该方法的灵敏度和特异度分别为80.4%和100%。拥有一种微创的“智能鞋底”设备，在现场进行血液荧光测试，将使加拿大妇女在自主控制的早期乳腺癌筛查中受益匪浅。该项目有三个组成部分：(A)科学(模拟执行器和随意行走对足部不同区域皮肤渗透的联合作用，以及估计血液采集量)；(B)开发(“智能鞋底”原型设计和优化)；(C)实验室和人体测试。在用于井下石油勘探的惯性导航系统(INS)领域，我的想法是将我的研究小组最新开发的钻井内对齐(IDA)技术应用于与现有非生产井的横向钻井偏差，同时提供INS胶囊的完整三维(3D)可控运动，以在这些偏差内钻头运动的所有三个平面上进行最大误差补偿。其目标是将IDA设置微型化，以适应12x100 mm的外壳，其中一个微型电机将提供受控的3D运动以进行误差补偿。还设想了基于中继的无线通信。该项目还有三个组成部分：(A)科学(模拟和量化3D控制运动对减少三架导航飞机导航误差的影响，并找到无线手段传递信息)；(B)开发(原型设计和优化)；(C)实验室和基础测试。该项目将对加拿大石油业和环境都有利，因为旧的停产油井将可以重复使用，避免新的油井钻探。