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Molecular characterization of the role of menin in embryonic development

Molecular characterization of the role of menin in embryonic development
Menin 在胚胎发育中作用的分子表征
批准号:
DP110105404
负责人:
Dr Graham Kay
金额:
$24.28万
依托单位国家:
澳大利亚
项目类别:
Discovery Projects
财政年份:
2011
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2011-01-01 至 2013-12-31

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中文摘要
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英文摘要
Menin is a protein that is necessary to prevent development of tumours. Deletion of menin in mice causes embryonic death. We think this is because menin is necessary in the placenta. This project will examine the role of menin in the fetus and the placenta, and provide information about how normal pregnancy and fetal growth is controlled.
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会议论文
Understanding the development of pancreatic islet cell tumours
Transcriptional targets of the MEN1 tumour suppressor in endocrine cancer
Microarray analysis of Vegf-b knockout mice.
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