Longitudinal investigation of the vaginal microbiota and its association with mucosal immune activation following human immunodeficiency virus vaccine vector administration

人类免疫缺陷病毒疫苗载体给药后阴道微生物群及其与粘膜免疫激活的关系的纵向研究

• 批准号: 406354
• 负责人: Shvartsman Elinor
• 金额: $ 1.27万
• 依托单位: University of Manitoba
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2018
• 资助国家: 加拿大
• 起止时间: 2018-12-01 至 2019-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=406354&lang=en
• 关键词: Cpn60; Dmpa; Hiv Prevention; Immune Activation; Inflammation; Kavi-Vzv001 Cohort; Longitudinal; Vaccine; Vaginal Microbiome; Women

Women are especially at high risk of Human immunodeficiency virus (HIV) acquisition due to the dynamic nature of the female genital tract (FGT). Bacterial Vaginosis (BV) is a microbial imbalance of the FGT characterized by a shift from a Lactobacillus dom

由于女性生殖道的动态性质，妇女感染人类免疫缺陷病毒(艾滋病毒)的风险尤其高。细菌性阴道病(Bv)是一种细菌性阴道病的微生物失衡，其特征是从乳杆菌菌群转移。