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Targeting Spliced X-Box Binding Protein 1 in Alternatively Activated Macrophages to prevent progression of lung fibrosis

Targeting Spliced X-Box Binding Protein 1 in Alternatively Activated Macrophages to prevent progression of lung fibrosis
靶向选择性激活的巨噬细胞中的剪接 X-Box 结合蛋白 1，以预防肺纤维化的进展
批准号：
406428
负责人：
Vierhout Megan J
金额：
$1.27万
依托单位：
McMaster University
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2018
资助国家：
加拿大
项目状态：
已结题
起止时间：
2018-12-01 至 2019-12-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=406428&lang=en
关键词：
Alternatively Activated Macrophages Endoplasmic Reticulum Stress Idiopathic Pulmonary Fibrosis Inositol Requiring Enzyme 1 Ire1 Inhibition Spliced X-Box Binding Protein 1 Target Identification Unfolded Protein Response

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中文摘要
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英文摘要
Fibroproliferative diseases, or diseases involving organ scarring and hardening, are associated with approximately 45% of deaths worldwide. Idiopathic Pulmonary Fibrosis (IPF) is a lung disease of unknown cause that leads to excessive scarring of the lung
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Characterizing the Role of Profibrotic Monocytes/Macrophages in the Progression of Fibrotic Lung Disease
  • 批准号：
    416720
  • 项目类别：
    Studentship Programs
  • 资助金额：
    $7.65万
  • 财政年份：
    2019
  • 负责人：
    Vierhout Megan J
  • 依托单位：
    McMaster University
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