Poly(ADP-ribose) writers, readers, and erasers: Functions in DNA double-strand break repair and synthetic lethality.
Poly(ADP-ribose) writers, readers, and erasers: Functions in DNA double-strand break repair and synthetic lethality.
批准号:
400856
负责人:
Poirier Guy G
金额:
$69.66万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2019
资助国家:
加拿大
项目状态:
已结题
起止时间:
2019-03-01 至 2024-03-01
中文摘要
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英文摘要
Inhibition of poly(ADP-ribose) polymerase (PARP) proteins, which cells use in a variety of DNA damage repair mechanisms, is a promising therapy for cancers. Because cancer cells often have preexisting defects in DNA damage repair pathways, the inhibition
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批准号:488326
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资助金额:$75.24万
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财政年份:2023
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负责人:Poirier Guy G
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依托单位:
Functions of poly(ADP-ribose) polymerases in DNA double-strand break processing and pathway choice
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批准号:290909
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项目类别:Operating Grants
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资助金额:$67.0万
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财政年份:2013
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负责人:Poirier Guy G
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依托单位:
Molecular mechanisms of cell death induced by poly(ADP-ribosyl)ation
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批准号:189171
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项目类别:Operating Grants
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资助金额:$45.87万
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财政年份:2009
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负责人:Poirier Guy G
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依托单位:
CANADA RESEARCH CHAIRHOLDER / TITULAIRE DE CHAIRE DE RECHERCHE DU CANADA
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批准号:204193
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项目类别:
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资助金额:$101.99万
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财政年份:2008
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负责人:Poirier Guy G
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依托单位:
Molecular mechanisms of cell death induced by poly(ADP-ribosyl)ation
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批准号:177931
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项目类别:Operating Grants
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资助金额:$7.29万
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财政年份:2008
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负责人:Poirier Guy G
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依托单位:
海外基金