Emerging roles of Zinc Finger PAR-Interacting Proteins (ZIPPs) in DNA double-strand break (DSB) repair: implications in PARPi therapy
Emerging roles of Zinc Finger PAR-Interacting Proteins (ZIPPs) in DNA double-strand break (DSB) repair: implications in PARPi therapy
批准号:
488326
负责人:
Poirier Guy G
金额:
$75.24万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2023
资助国家:
加拿大
项目状态:
未结题
起止时间:
2023-09-01 至 2028-09-01
中文摘要
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英文摘要
PARP inhibitors (PARPi) and agents that target the DNA damage response (DDR) have been shown to be useful for the treatment of a number of tumor types. In some cancers they can be used as an alternative to chemotherapy. In others, these drugs can be used
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依托单位:
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依托单位:
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项目类别:
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资助金额:$101.99万
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依托单位:
Molecular mechanisms of cell death induced by poly(ADP-ribosyl)ation
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负责人:Poirier Guy G
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依托单位:
海外基金