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Molecular and Translational Studies of Filamin Signaling Network in Invasive Cancer

Molecular and Translational Studies of Filamin Signaling Network in Invasive Cancer
侵袭性癌症中细丝蛋白信号网络的分子和转化研究
批准号：
205082
负责人：
Alaoui-Jamali Moulay A
金额：
$7.29万
依托单位：
Lady Davis Institute for Medical Research (Mtl)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2009
资助国家：
加拿大
项目状态：
已结题
起止时间：
2009-09-01 至 2010-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=205082&lang=en
关键词：
Cancer Cell Cytoskeleton Cell Invasion Metastasis Formation Molecular And Cellular Biology Protein Dynamics

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英文摘要
Excessive cell locomotion and motile properties are among the earliest events by which cancer cells can spread and invade distant organs (referred to as metastasis formation). Cancer cell movement and cell migration are controlled by sophisticated and dyn
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Characterization and therapeutic implication of a novel class of PKC-theta inhibitors selectively targeting undifferentiated cancer cells expressing stem cell markers
Triple Targeted Kinase Inhibitors Capable of Inhibiting Breast Cancer Metastases
Investigation of the Filamin Signaling Network's Function in Cancer Progression
Discovery and Validation of Pharmacological Probes for Understanding Protein-Protein Interactions of Focal Adhesion Signalling in Invasive Cancer Cells
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