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Molecular Mechanisms of Substrate Binding and Activity of the Human Terminal Nucleotidyltransferase Gld2 (germline-development 2)

人末端核苷酸转移酶 Gld2 的底物结合和活性的分子机制（种系发育 2）

基本信息

批准号：
504523-2017
负责人：
Chung, Christina
金额：
$ 0.85万
依托单位：
University of Western Ontario
依托单位国家：
加拿大
项目类别：
Alexander Graham Bell Canada Graduate Scholarships - Doctoral
财政年份：
2019
资助国家：
加拿大
起止时间：
2019-01-01 至 2020-12-31
项目状态：
已结题

来源：
https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=674447
关键词：
Molecular Mechanisms Substrate Binding Activity

项目摘要

nucleotidyltransferase, adenylyltransferase, RNA, post-translational modification, phosphorylation, crystallization, biotinylation

核苷酸转移酶，腺苷酰转移酶，RNA，翻译后修饰，磷酸化，结晶，生物素化

项目成果

期刊论文数量（0）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

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Chung, Christina其他文献

The Yeast Cap Binding Complex Modulates Transcription Factor Recruitment and Establishes Proper Histone H3K36 Trimethylation during Active Transcription

DOI：
10.1128/mcb.00947-12
发表时间：
2013-02-01
期刊：
MOLECULAR AND CELLULAR BIOLOGY
影响因子：
5.3
作者：
Hossain, Munshi Azad;Chung, Christina;Johnson, Tracy L.
通讯作者：
Johnson, Tracy L.

The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis.

DOI：
10.1016/s0140-6736(12)60110-x
发表时间：
2012-03-31
期刊：
LANCET
影响因子：
168.9
作者：
Swerdlow, Daniel I.;Holmes, Michael V.;Kuchenbaecker, Karoline B.;Engmann, Jorgen E. L.;Shah, Tina;Sofat, Reecha;Guo, Yiran;Chung, Christina;Peasey, Anne;Ster, Roman Pfi;Mooijaart, Simon P.;Ireland, Helen A.;Leusink, Maarten;Langenberg, Claudia;Li, KaWah;Palmen, Jutta;Howard, Philip;Cooper, Jackie A.;Drenos, Fotios;Hardy, John;Nalls, Michael A.;Li, Yun Rose;Lowe, Gordon;Stewart, Marlene;Bielinski, Suzette J.;Peto, Julian;Timpson, Nicholas J.;Gallacher, John;Dunlop, Malcolm;Houlston, Richard;Tomlinson, Ian;Tzoulaki, Ioanna;Luan, Jian'an;Boer, Jolanda M. A.;Forouhi, Nita G.;Onland-Moret, N. Charlotte;van der Schouw, Yvonne T.;Schnabel, Renate B.;Hubacek, Jaroslav A.;Kubinova, Ruzena;Baceviciene, Migle;Tamosiunas, Abdonas;Pajak, Andrzej;Topor-Madry, Roman;Malyutina, Sofi A.;Baldassarre, Damiano;Sennblad, Bengt;Tremoli, Elena;de Faire, Ulf;Ferrucci, Luigi;Bandenelli, Stefania;Tanaka, Toshiko;Meschia, James F.;Singleton, Andrew;Navis, Gerjan;Leach, Irene Mateo;Bakker, Stephan J. L.;Gansevoort, Ron T.;Ford, Ian;Epstein, Stephen E.;Burnett, Mary Susan;Devaney, Joe M.;Jukema, J. Wouter;Westendorp, Rudi G. J.;de Borst, Gert Jan;van der Graaf, Yolanda;de Jong, Pim A.;Maitland-van der Zee, Anke-Hilse;Klungel, Olaf H.;de Boer, Anthonius;Doevendans, Pieter A.;Stephens, Jeffrey W.;Eaton, Charles B.;Robinson, Jennifer G.;Manson, JoAnn E.;Fowkes, F. Gerry R.;Frayling, Timothy M.;Price, Jackie F.;Whincup, Peter H.;Morris, Richard W.;Lawlor, Debbie A.;Smith, George Davey;Ben-Shlomo, Yoav;Redline, Susan;Lange, Leslie A.;Kumari, Meena;Wareham, Nick J.;Verschuren, W. M. Monique;Benjamin, Emelia J.;Whittaker, John C.;Hamsten, Anders;Dudbridge, Frank;Delaney, J. A. Chris;Wong, Andrew;Kuh, Diana;Hardy, Rebecca;Castillo, Berta Almoguera;Connolly, John J.;van der Harst, Pim;Brunner, Eric J.;Marmot, Michael G.;Wassel, Christina L.;Humphries, Steve E.;Talmud, Philippa J.;Kivimaki, Mika;Asselbergs, Folkert W.;Voevoda, Mikhail;Bobak, Martin;Pikhart, Hynek;Wilson, James G.;Hakonarson, Hakon;Reiner, Alex P.;Keating, Brendan J.;Sattar, Naveed;Hingorani, Aroon D.;Casas, Juan Pablo
通讯作者：
Casas, Juan Pablo

Pandemic play moderates the relation between caregiver stress and child emotional distress in contexts of economic adversity.

DOI：
10.3389/fpsyg.2023.1155617
发表时间：
2023
期刊：
FRONTIERS IN PSYCHOLOGY
影响因子：
3.8
作者：
Rueda-Posada, Maria Fernanda;Thibodeau-Nielsen, Rachel B.;Dier, Shannon E.;Wilson-Dooley, Alaina;Palermo, Francisco;White, Rachel E.;Chung, Christina
通讯作者：
Chung, Christina

HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials.

DOI：
10.1016/s0140-6736(14)61183-1
发表时间：
2015-01-24
期刊：
LANCET
影响因子：
168.9
作者：
Swerdlow, Daniel I.;Preiss, David;Kuchenbaecker, Karoline B.;Holmes, Michael V.;Engmann, Jorgen E. L.;Shah, Tina;Sofat, Reecha;Stender, Stefan;Johnson, Paul C. D.;Scott, Robert A.;Leusink, Maarten;Verweij, Niek;Sharp, Stephen J.;Guo, Yiran;Giambartolomei, Claudia;Chung, Christina;Peasey, Anne;Amuzu, Antoinette;Li, Kawah;Palmen, Jutta;Howard, Philip;Cooper, Jackie A.;Drenos, Fotios;Li, Yun R.;Lowe, Gordon;Gallacher, John;Stewart, Marlene C. W.;Tzoulaki, Ioanna;Buxbaum, Sarah G.;Daphne, L. van der A.;Forouhi, Nita G.;Onland-Moret, N. Charlotte;van der Schouw, Yvonne T.;Schnabel, Renate B.;Hubacek, Jaroslav A.;Kubinova, Ruzena;Baceviciene, Migle;Tamosiunas, Abdonas;Pajak, Andrzej;Topor-Madry, Roman;Stepaniak, Urszula;Malyutina, Sofi A.;Baldassarre, Damiano;Sennblad, Bengt;Tremoli, Elena;de Faire, Ulf;Veglia, Fabrizio;Ford, Ian;Jukema, J. Wouter;Westendorp, Rudi G. J.;de Borst, Gert Jan;de Jong, Pim A.;Algra, Ale;Spiering, Wilko;Maitland-van der Zee, Anke H.;Klungel, Olaf H.;de Boer, Anthonius;Doevendans, Pieter A.;Eaton, Charles B.;Robinson, Jennifer G.;Duggan, David;Kjekshus, John;Downs, John R.;Gotto, Antonio M.;Keech, Anthony C.;Marchioli, Roberto;Tognoni, Gianni;Sever, Peter S.;Poulter, Neil R.;Waters, David D.;Pedersen, Terje R.;Amarenco, Pierre;Nakamura, Haruo;McMurray, John J. V.;Lewsey, James D.;Chasman, Daniel I.;Ridker, Paul M.;Maggioni, Aldo P.;Tavazzi, Luigi;Ray, Kausik K.;Seshasai, Sreenivasa Rao Kondapally;Manson, Joann E.;Price, Jackie F.;Whincup, Peter H.;Morris, Richard W.;Lawlor, Debbie A.;Smith, George Davey;Ben-Shlomo, Yoav;Schreiner, Pamela J.;Fornage, Myriam;Siscovick, David S.;Cushman, Mary;Kumari, Meena;Wareham, Nick J.;Verschuren, W. M. Monique;Redline, Susan;Patel, Sanjay R.;Whittaker, John C.;Hamsten, Anders;Delaney, Joseph A.;Dale, Caroline;Gaunt, Tom R.;Wong, Andrew;Kuh, Diana;Hardy, Rebecca;Kathiresan, Sekar;Castillo, Berta A.;van der Harst, Pim;Brunner, Eric J.;Tybjaerg-Hansen, Anne;Marmot, Michael G.;Krauss, Ronald M.;Tsai, Michael;Coresh, Josef;Hoogeveen, Ronald C.;Psaty, Bruce M.;Lange, Leslie A.;Hakonarson, Hakon;Dudbridge, Frank;Humphries, Steve E.;Talmud, Philippa J.;Kivimaeki, Mika;Timpson, Nicholas J.;Langenberg, Claudia;Asselbergs, Folkert W.;Voevoda, Mikhail;Bobak, Martin;Pikhart, Hynek;Wilson, James G.;Reiner, Alex P.;Keating, Brendan J.;Hingorani, Aroon D.;Sattar, Naveed
通讯作者：
Sattar, Naveed