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Tumour-suppressive regulation of the Wnt/ß-catenin signaling pathway by the CTLH complex

Tumour-suppressive regulation of the Wnt/ß-catenin signaling pathway by the CTLH complex
CTLH 复合物对 Wnt/α-catenin 信号通路的肿瘤抑制调节
批准号:
409020
负责人:
Schild-Poulter Caroline
金额:
$58.8万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2019
资助国家:
加拿大
项目状态:
已结题
起止时间:
2019-09-01 至 2024-09-01

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中文摘要
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英文摘要
Cancer is a multistep process that leads to cellular alterations that transform normal cells into malignant cells. Dysregulation of the Wnt/ß-catenin pathway is one of the most frequent cellular events in the initiation and progression of carcinogenesis i
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Investigating the molecular pathology of WDR26 deficiency
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    472604
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    $7.29万
  • 财政年份:
    2022
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Cell signaling pathway regulation by the RanBPM/CTLH complex in cancer development
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    322654
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    2015
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Characterization of RanBPM function in apoptosis and cell transformation
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    225435
  • 项目类别:
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  • 资助金额:
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  • 财政年份:
    2011
  • 负责人:
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  • 依托单位:
Mechanisms of RanBPM-mediated cell death
  • 批准号:
    199405
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  • 依托单位:
海外基金