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Mutation co-operativity in early tumorigenesis events of low-grade serous ovarian carcinoma: Lesson from an organoid model system and single-cell RNA-sequencing

Mutation co-operativity in early tumorigenesis events of low-grade serous ovarian carcinoma: Lesson from an organoid model system and single-cell RNA-sequencing
低级别浆液性卵巢癌早期肿瘤发生事件中的突变协同性：类器官模型系统和单细胞 RNA 测序的教训
批准号：
412074
负责人：
Zhang Joyce (Yu Han)
金额：
$0.11万
依托单位：
B.C. Cancer Research Centre (Vancouver)
依托单位国家：
加拿大
项目类别：
财政年份：
2019
资助国家：
加拿大
项目状态：
已结题
起止时间：
2019-09-01 至 2020-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=412074&lang=en
关键词：
Diagnostic Markers Ics Travel Awards Modelling Tumorigenesis Events Organoid Culture Ovarian Cancer Single-Cell Rna-Sequencing Targeted Treatment Options

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英文摘要
Ovarian cancer is the most common gynecologic cancer and the fifth leading cause of cancer death in women. Such poor outcome is due to lack of reliable early detection strategies and suboptimal response to chemotherapies. Our study focuses on a rare subty
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Dicing the tumorigenesis trajectory of DICER1 syndrome with novel murine model
  • 批准号：
    476158
  • 项目类别：
    Studentship Programs
  • 资助金额：
    $7.65万
  • 财政年份：
    2022
  • 负责人：
    Zhang Joyce (Yu Han)
  • 依托单位：
    University of British Columbia
Modelling Serous Cancers of the Mullerian Tract using Organoids
  • 批准号：
    406486
  • 项目类别：
    Studentship Programs
  • 资助金额：
    $1.27万
  • 财政年份：
    2018
  • 负责人：
    Zhang Joyce (Yu Han)
  • 依托单位：
    University of British Columbia
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