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Dicing the tumorigenesis trajectory of DICER1 syndrome with novel murine model

Dicing the tumorigenesis trajectory of DICER1 syndrome with novel murine model
用新型小鼠模型切分 DICER1 综合征的肿瘤发生轨迹
批准号：
476158
负责人：
Zhang Joyce (Yu Han)
金额：
$7.65万
依托单位：
University of British Columbia
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2022
资助国家：
加拿大
项目状态：
未结题
起止时间：
2022-11-01 至 2025-11-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=476158&lang=en
关键词：
Microrna Processing Dysregulation Modelling Tumorigenesis Events Single-Cell Microrna Sequencing Single-Cell Rna Sequencing Transgenic Mouse Model

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中文摘要
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英文摘要
DICER1 syndrome is a rare genetic condition linked with frequent mutations (changes) in the DICER1 gene and an increased risk for developing tumours in various organs such as the kidneys, lungs, ovaries, thyroid; by age 60, the risk of having a malignancy
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会议论文
Mutation co-operativity in early tumorigenesis events of low-grade serous ovarian carcinoma: Lesson from an organoid model system and single-cell RNA-sequencing
Modelling Serous Cancers of the Mullerian Tract using Organoids
  • 批准号：
    406486
  • 项目类别：
    Studentship Programs
  • 资助金额：
    $1.27万
  • 财政年份：
    2018
  • 负责人：
    Zhang Joyce (Yu Han)
  • 依托单位：
    University of British Columbia