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Deciphering recurrence of glioblastoma for precision medicine using multi-omics data integration

Deciphering recurrence of glioblastoma for precision medicine using multi-omics data integration
利用多组学数据集成破译胶质母细胞瘤的复发以实现精准医疗
批准号：
411363
负责人：
Reimand Jüri
金额：
$16.39万
依托单位：
Ontario Institute for Cancer Research (Toronto, Ontario)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2019
资助国家：
加拿大
项目状态：
已结题
起止时间：
2019-09-01 至 2022-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=411363&lang=en
关键词：
Bioinformatics Cancer Driver Mutations Data Integration Glioblastoma Proteogenomics Recurrence And Metastasis Sub-Clonal Reconstruction Tumor Evolution Whole Genome Sequencing

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英文摘要
Glioblastoma (GBM) is the most lethal form of brain tumor. On average, patients survive only 15 months after diagnosis because most tumors inevitably recur after surgery. Intra-tumor heterogeneity is believed to cause this dismal outcome: GBMs are complex
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