Dissecting the mechanisms and long-term impact of activation of transposons by gestational stress

剖析妊娠应激激活转座子的机制和长期影响

• 批准号: 413905
• 负责人: Sultana Tania
• 金额: $ 10.2万
• 依托单位: Lunenfeld-Tanenbaum Research Institute (Toronto)
• 依托单位国家: 加拿大
• 项目类别: Fellowship Programs
• 财政年份: 2019
• 资助国家: 加拿大
• 起止时间: 2019-09-01 至 2021-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=413905&lang=en
• 关键词: Dutch Hunger Winter; Embryonic Stem Cells; Environmental Factors; Human Genome; Stress; Transposable Elements

Pregnancy represents the most critical period to impact health throughout life. Embryo and fetus are sensitive to environmental factors such as nutritional deficits or exposure to toxins that can have long-term consequences for disease propensity into adu

怀孕是影响一生健康的最关键时期。胚胎和胎儿对环境因素很敏感，如营养缺乏或暴露于毒素，这些因素可能会对疾病倾向产生长期影响。