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Host response modulation results in altered Ebola virus replication and transcription kinetics in immune-privileged testis, which facilitates asymptomatic and persistent infections that may affect reproductive health and sexual transmission

Host response modulation results in altered Ebola virus replication and transcription kinetics in immune-privileged testis, which facilitates asymptomatic and persistent infections that may affect reproductive health and sexual transmission
宿主反应调节导致免疫特权睾丸中埃博拉病毒复制和转录动力学改变，从而促进无症状和持续感染，可能影响生殖健康和性传播
批准号：
418113
负责人：
Webb Andrew L
金额：
$7.65万
依托单位：
University of Manitoba
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2019
资助国家：
加拿大
项目状态：
已结题
起止时间：
2019-10-01 至 2022-10-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=418113&lang=en
关键词：
Ebola Virus Host Response Immune Privilege Kinomics Persistent Infection Rna Sequencing Testicular Infection Transcriptomics Viral Replication

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The current Ebola virus disease outbreak in the Democratic Republic of Congo has resulted in more than 2,900 infections and 1,900 fatalities, with no end in sight. This outbreak is already the second largest in history; the largest only ended three years
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