Quantum dot lighting solutions for optogenetics and precision growth of photosynthetic organisms

点击翻译按钮获取中文摘要

Sunlight influences circadian rhythms that regulate the timing of biological processes and behaviour in humans. Conventional office and computer lighting does not follow this cycle, upsetting the performance of our biological clock and affecting our sleep. This effects performance, mood and health. Nano-Lit Technologies has developed a control system that works in combination with a Quantum Dot LED lighting system to provide customers superior lighting systems for our biological needs. The most significant challenge currently facing the lighting industry is quantifiably proving the efficacy of controlled lighting on health, sleep quality and energy levels. This research project will develop a laboratory-scale lighting system based onNano-Lit's core technology that will enable us to test organismal responsiveness to quantum dot lighting in high-throughput, using the light-dependant genetic circuits in photosynthetic organisms and optogenetics, as proxies for those that exist in plants and animals, including humans. We will design, develop and test quantum dot-based lighting solutions that can be integrated into the Labcyte Access Workstation high-throughput screening instrumentation in the Hallam lab, enabling automated plating, incubation and monitoring of up to 40,320 clonal cultures in parallel. These efforts will provide Nano-Lit with quantitative information on the efficacy of their Quantum Dot LED lighting system.