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Role and regulatory mechanisms of pre- versus post-synaptic mRNA translation in memory formation and retrieval within glutamatergic neurons of an intact neural circuit

Role and regulatory mechanisms of pre- versus post-synaptic mRNA translation in memory formation and retrieval within glutamatergic neurons of an intact neural circuit
完整神经回路谷氨酸能神经元内突触前与突触后 mRNA 翻译在记忆形成和检索中的作用和调节机制
批准号：
412292
负责人：
Cagnetta Roberta
金额：
$9.83万
依托单位：
McGill University
依托单位国家：
加拿大
项目类别：
Fellowship Programs
财政年份：
2019
资助国家：
加拿大
项目状态：
已结题
起止时间：
2019-10-01 至 2022-10-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=412292&lang=en
关键词：
Adeno-Associated Virus-Based Gene Targeting 'In Vivo' Fluorescence Activated Synaptosome Sorting 'In Vivo' Glutamatergic Neurons Local Mrna Translation Memory Formation And Retrieval Neural Circuit Maintenance And Remodelling Pre- And Post-Synaptic

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英文摘要
One of the most fundamental properties of the brain is the ability to make and recall memories, from minutes to years. The incidence of memory impairment (~8% among Canadians aged 75 and older) is escalating with population aging. To tackle this problem i
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Role and regulatory mechanisms of pre- versus post-synaptic mRNA translation in remote memory recall at single neuron type resolution 'in vivo'
  • 批准号：
    473841
  • 项目类别：
    Fellowship Programs
  • 资助金额：
    $3.28万
  • 财政年份：
    2022
  • 负责人：
    Cagnetta Roberta
  • 依托单位：
    McGill University
Role and regulatory mechanisms of pre- versus post-synaptic mRNA translation in memory formation and retrieval within glutamatergic neurons of an intact neural circuit
  • 批准号：
    411619
  • 项目类别：
    Fellowship Programs
  • 资助金额：
    $10.2万
  • 财政年份：
    2019
  • 负责人：
    Cagnetta Roberta
  • 依托单位：
    McGill University