Granzyme B: A Novel Therapeutic Target for Bullous Pemphigoid

颗粒酶 B：大疱性类天疱疮的新治疗靶点

• 批准号: 412458
• 负责人: Hiroyasu Sho
• 金额: $ 9.83万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Fellowship Programs
• 财政年份: 2019
• 资助国家: 加拿大
• 起止时间: 2019-10-01 至 2022-10-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=412458&lang=en
• 关键词: Autoimmune Blistering Diseases; Bullous Pemphigoid; Cell Adhesion; Dermatology; Extracellular Matrix; Granzyme B; Hemidesmosome; Mouse Models; Proteomics; Skin Biology

Bullous pemphigoid - Skin blisters occur when layers of the skin separate and body fluid collects in a pocket formed between the skin layers. While most of us have had blisters caused by friction, sunburns, or infections, some patients suffer from conditi

大疱性类天疱疮-皮肤水疱发生时，皮肤层分离和体液收集在一个口袋之间形成的皮肤层。虽然我们中的大多数人都有过由摩擦、晒伤或感染引起的水泡，但也有一些患者患有条件反射。