IONOS: An Iono-Electronic Interface for Communication with Living Systems

IONOS：用于与生命系统通信的离子电子接口

• 批准号: RGPIN-2018-05372
• 负责人: Alibart, Fabien
• 金额: $ 2.04万
• 依托单位: Université de Sherbrooke
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2019
• 资助国家: 加拿大
• 起止时间: 2019-01-01 至 2020-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=682501
• 关键词: IONOS; Iono; Electronic; Interface; Communication

While our understanding of the brain has made huge progresses, we are still inefficient in interfacing biological systems with electronics, both in terms of energy and integration potential. Pushed by the need to use conventional computers for building complex systems dedicated to brain interface applications, we have mostly capitalized on technologies and architectures inherited from microelectronic that are intrinsically not adapted to interface living systems. The IONOS research program will shift the brain interface paradigm by developing new technologies designed to interact intimately with biological cells and capitalizing heavily on bio-inspiration. To reach this goal, IONOS will explore how to sense, stimulate and compute biological signals from in-vitro neural cells' assembly based on iono-electronic materials and devices. These emerging devices offer basics functionalities such as memory, ion-electron signal's transduction, and amplification paving the way to a new field of device and circuit engineering that could efficiently reproduce key biological functions such as learning and spatio-temporal processing of information. This program will demonstrate how these concepts associated to the bio-inspired computing paradigm can unlock our fundamental limitations for communicating with living neural cells. Proof of concept will show how an artificial system can efficiently send, receive and compute information from a biological one, which constitutes the basic of communication.

虽然我们对大脑的理解已经取得了巨大的进步，但我们在生物系统与电子设备的接口方面仍然效率低下，无论是在能量方面还是在集成潜力方面。在使用传统计算机构建专门用于脑接口应用的复杂系统的需求的推动下，我们主要利用了继承自微电子的技术和架构，这些技术和架构本质上不适合与生活系统进行接口。IONOS研究计划将通过开发旨在与生物细胞密切互动的新技术，并大量利用生物灵感，来改变大脑接口范式。为了实现这一目标，IONOS将探索如何基于离子电子材料和设备从体外神经细胞组装中感知、刺激和计算生物信号。这些新兴的设备提供了基本的功能，如记忆、离子电子信号的转换和放大，为进入一个新的设备和电路工程领域铺平了道路，该领域可以有效地复制关键的生物功能，如学习和信息的时空处理。这个项目将展示这些与生物启发的计算范例相关的概念如何解锁我们与活的神经细胞交流的基本限制。概念证明将展示人工系统如何有效地发送、接收和计算来自生物系统的信息，这构成了通信的基础。