Defining the role of BRCA2-deficient mammary stromal fibroblasts in the growth and transformation of mammary epithelial cells.

定义 BRCA2 缺陷型乳腺基质成纤维细胞在乳腺上皮细胞生长和转化中的作用。

• 批准号: 429059
• 负责人: Whitney Rachael
• 金额: $ 1.27万
• 依托单位: University of Ottawa
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2019
• 资助国家: 加拿大
• 起止时间: 2019-12-01 至 2020-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=429059&lang=en
• 关键词: Brca2; Breast Cancer; Dna Damage; Genetics

"Individuals who carry mutations in the DNA repair gene known as BRCA2, have a higher lifetime risk of developing breast cancer compared to those who do not carry the mutated version of the gene. In order to develop successful strategies for risk assessme

“与不携带突变基因的人相比，携带BRCA2 DNA修复基因突变的人患乳腺癌的终生风险更高。为了制定成功的风险评估策略，