Innovation through design: 3D printing and desktop injection molding system for biomedical applications

通过设计进行创新：用于生物医学应用的 3D 打印和桌面注塑系统

• 批准号: RTI-2020-00667
• 负责人: Mclean, Linda
• 金额: $ 2.84万
• 依托单位: University of Ottawa
• 依托单位国家: 加拿大
• 项目类别: Research Tools and Instruments
• 财政年份: 2019
• 资助国家: 加拿大
• 起止时间: 2019-01-01 至 2020-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=687470
• 关键词: Innovation; through; design; 3D; printing

Silicone injection molding is an essential need in the NSERC Discovery Grant Programs of Drs. McLean and Labrosse, yet up until now, such capacity has been out of reach. To date, machines have been large and very costly, with limited versatility as they are tuned to specific applications. Indeed injection molding systems have had limited value as an infrastructure investment for academic researchers. Just this year however, the first desktop injection molding system compatible with silicone was launched by Structur3D, a Canadian company. A second desktop system is also soon to be available by APSX-PIM. Such emerging technology is essential to support the development of devices to meet urgent research needs of Drs. McLean, Labrosse and others.***Dr. McLean's NSERC DG program is actively focusing on device design for commercialization. She currently requires capacity for rapid prototyping of device parts in plastic (ABS/PLA) and in medical grade silicone needs that she cannot meet with tools available in her lab or more generally on campus. Through his NSERC DG program, Dr. Labrosse is developing, testing and validating new tools to help cardiac surgeons with the planning of repair procedures on the aortic valves. He urgently needs to generate aortic valve models that will be used both as surrogates for surgical training, as well as to verify and validate advanced computer simulation tools for the planning of aortic valve repair. The Structur3D system is ideal for these applications as models can easily be refined using several design iterations and material properties. This flexibility will also facilitate sharing with several identified users who require access to 3D print capability using dual extrusion or to prototype devices using injection molding. This is an ideal infrastructure investment. ***The proposed Structur3D system includes an Ultimaker S5 dual extrusion 3D printer, ultrasonic bath and vacuum hood coupled with the Discov3ry automated, dual extrusion injection molding system. This system is truly state-of-the art. The product, just launched in October 2019, will allow researchers to generate their own molds and mix their own materials to customize properties to their applications. In the case of Dr. McLean's work, the system allows her to use medical grade silicone (i.e., Nusil), an essential material for her devices. ***Both Drs. McLean and Labrosse have excellent mentoring records and strive to recruit and support their HQP through processes that reflect the principles of equity, diversity and inclusion. The requested on-site training will ensure that trainees quickly become competent at rapid prototyping. This will generate a local pool of highly qualified personnel who can train and mentor new users. HQP will learn advanced approaches to iterative device design, prototyping and testing in a real-world environment skills that are highly transferable to the rapidly evolving area of biomedical device design and optimization.*****

有机硅注射成型是姆克林和Labrosse博士的NSERC发现资助计划的基本需求，但到目前为止，这种能力还无法达到。到目前为止，机器已经很大，非常昂贵，具有有限的通用性，因为它们被调整到特定的应用。 事实上，注塑成型系统作为学术研究人员的基础设施投资价值有限。然而就在今年，加拿大公司Structur 3D推出了第一个与硅胶兼容的桌面注塑系统。 第二个桌面系统也将很快由APSX-PIM提供。 这种新兴技术对于支持设备开发以满足姆克林、Labrosse等人的紧迫研究需求至关重要。*姆克林博士的NSERC DG计划积极关注商业化的设备设计。 她目前需要塑料（ABS/PLA）设备部件的快速原型制作能力，以及她无法在实验室或校园内使用工具满足的医疗级硅胶需求。 通过他的NSERC DG计划，Labrosse博士正在开发，测试和验证新的工具，以帮助心脏外科医生规划主动脉瓣修复手术。他迫切需要生成主动脉瓣模型，这些模型将用作手术培训的替代品，并用于验证和验证用于主动脉瓣修复计划的先进计算机模拟工具。Structur 3D系统是这些应用的理想选择，因为模型可以使用几个设计迭代和材料属性轻松细化。这种灵活性还将有助于与几个需要使用双挤出获得3D打印功能或使用注塑成型获得原型设备的用户进行共享。这是一项理想的基础设施投资。* 拟议的Structur 3D系统包括Ultimaker S5双挤出3D打印机、超声波浴和真空罩，以及Discov 3ry自动化双挤出注塑成型系统。该产品于2019年10月刚刚推出，将允许研究人员生成自己的模具并混合自己的材料，以根据其应用定制性能。 在姆克林博士的工作中，该系统允许她使用医用级硅胶（即，Nusil），这是她的设备的基本材料。*** 姆克林博士和Labrosse博士都有出色的指导记录，并努力通过反映公平，多样性和包容性原则的流程招聘和支持他们的HQP。 所要求的现场培训将确保受训人员迅速胜任快速原型制作工作。这将产生一批能够培训和指导新用户的高素质人员。HQP将学习先进的方法来迭代设备设计，原型设计和测试在现实世界的环境中的技能，这些技能高度转移到生物医学设备设计和优化的快速发展领域。