The impact of Nod proteins on the inflammatory response to differentially compartmentalized intracellular pathogens

Nod蛋白对不同细胞内病原体炎症反应的影响

• 批准号: 189709
• 负责人: Philpott Dana J
• 金额: $ 51.36万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2009
• 资助国家: 加拿大
• 起止时间: 2009-09-01 至 2014-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=189709&lang=en
• 关键词: Cell Biology; Immunity; Infection; Inflammation; Inflammatory Bowel Disease

Detection of microbes by the host is critical to initiate a program to develop inflammation, leading to the successful clearance of the infection. Specific receptors inside the host cell are critical for the initiation of this program. Our laboratory stud

宿主对微生物的检测对于启动炎症发展程序至关重要，从而导致感染的成功清除。宿主细胞内的特异性受体对于启动该程序至关重要。我们的实验室研究