A novel role for IL-18 in the control of the intestinal epithelium during infection and inflammation.
IL-18 在感染和炎症期间控制肠上皮的新作用。
基本信息
- 批准号:462743
- 负责人:
- 金额:$ 66.88万
- 依托单位:
- 依托单位国家:加拿大
- 项目类别:Operating Grants
- 财政年份:2022
- 资助国家:加拿大
- 起止时间:2022-03-01 至 2027-03-01
- 项目状态:未结题
- 来源:
- 关键词:
项目摘要
Intestinal inflammation due to infection or diseases like inflammatory bowel disease causes great deal of morbidity and mortality. Our recent work has uncovered a novel pathway in the intestine that protects against infection. Interesting also is that dy
由于感染或炎症性肠病等疾病引起的肠道炎症导致大量的发病率和死亡率。我们最近的工作揭示了肠道中一种新的保护免受感染的途径。有趣的是,
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Philpott Dana J其他文献
Philpott Dana J的其他文献
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{{ truncateString('Philpott Dana J', 18)}}的其他基金
New insights into the development of metabolic dysfunction as a comorbidity in Crohn's disease.
关于代谢功能障碍作为克罗恩病合并症的发展的新见解。
- 批准号:
493720 - 财政年份:2023
- 资助金额:
$ 66.88万 - 项目类别:
Operating Grants
Investigating the role of NOD2 in intestinal fibrosis
研究NOD2在肠纤维化中的作用
- 批准号:
488109 - 财政年份:2023
- 资助金额:
$ 66.88万 - 项目类别:
Operating Grants
The role of NOD2 in intestinal regeneration following injury
NOD2在损伤后肠道再生中的作用
- 批准号:
445536 - 财政年份:2021
- 资助金额:
$ 66.88万 - 项目类别:
Operating Grants
Synthetic biology approaches to design living medicines to improve intestinal and metabolic health.
采用合成生物学方法设计活体药物以改善肠道和代谢健康。
- 批准号:
415634 - 财政年份:2019
- 资助金额:
$ 66.88万 - 项目类别:
Operating Grants
Canada Research Chair - Tier 1 - CIHR Funded
加拿大研究主席 - 一级 - CIHR 资助
- 批准号:
384878 - 财政年份:2017
- 资助金额:
$ 66.88万 - 项目类别:
Innate immune regulation of intestinal homeostasis: insight into Crohn's disease pathogenesis.
肠道稳态的先天免疫调节:深入了解克罗恩病发病机制。
- 批准号:
312754 - 财政年份:2014
- 资助金额:
$ 66.88万 - 项目类别:
Operating Grants
Nod-like receptors: linking innate immunity and inflammation to chronic disease
Nod 样受体:将先天免疫和炎症与慢性疾病联系起来
- 批准号:
296540 - 财政年份:2013
- 资助金额:
$ 66.88万 - 项目类别:
Operating Grants
Nod-like receptors: linking innate immunity and inflammation to chronic disease
Nod 样受体:将先天免疫和炎症与慢性疾病联系起来
- 批准号:
276515 - 财政年份:2012
- 资助金额:
$ 66.88万 - 项目类别:
Operating Grants
Role of Nod proteins in mucosal defense against bacterial pathogens
Nod 蛋白在粘膜防御细菌病原体中的作用
- 批准号:
254793 - 财政年份:2012
- 资助金额:
$ 66.88万 - 项目类别:
Operating Grants
16th International Congress of Mucosal Immunology (ICMI 2013)
第十六届国际粘膜免疫学大会(ICMI 2013)
- 批准号:
273213 - 财政年份:2012
- 资助金额:
$ 66.88万 - 项目类别:
Miscellaneous Programs
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基于纤维化相关蛋白抑制剂 (FAPI) 的放射性示踪成像,可识别肠道克罗恩病 (FATE-CD) 中的纤维化活动
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New insights into the development of metabolic dysfunction as a comorbidity in Crohn's disease.
关于代谢功能障碍作为克罗恩病合并症的发展的新见解。
- 批准号:
493720 - 财政年份:2023
- 资助金额:
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儿童克罗恩病身高发育障碍的性别差异:第 2 部分
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10638422 - 财政年份:2023
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解构克罗恩病的纤维化微环境,促进组织愈合
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