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Prevalence, Burden and Reversal of Stringent Response-Mediated Antibiotic Tolerance

Prevalence, Burden and Reversal of Stringent Response-Mediated Antibiotic Tolerance
严格反应介导的抗生素耐受性的患病率、负担和逆转
批准号：
418571
负责人：
Boraston Alisdair B
金额：
$47.93万
依托单位：
University of Victoria (British Columbia)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2020
资助国家：
加拿大
项目状态：
未结题
起止时间：
2020-03-01 至 2025-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=418571&lang=en
关键词：
Antibiotic Resistance Antibiotic Tolerance Bacteremia Clinical Isolates Cystic Fibrosis Enterococci Mutation Persistent Infections Staphylococcus Aureus Stringent Response

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Bacterial infections are a leading cause of hospitalization and death worldwide. Antibiotics are central to our ability to treat bacterial infections, but our capacity to cure these infections is jeopardized by increasing antibiotic resistance (where bact
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