课题基金 / 基金详情

Single turnover covalent chaperones for disease related lysosomal enzymes

Single turnover covalent chaperones for disease related lysosomal enzymes
疾病相关溶酶体酶的单周转共价伴侣
批准号：
421413
负责人：
Bennet Andrew J
金额：
$73.84万
依托单位：
Simon Fraser University (Burnaby, B.C.)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2020
资助国家：
加拿大
项目状态：
未结题
起止时间：
2020-03-01 至 2025-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=421413&lang=en
关键词：
Chemical Chaperones Covalent Inhibitors Folding Glucocerebrosidase Glycoside Hydrolases Live Cell Imaging Lysosomal Storage Diseases Mechanism Based Parkinson'S Trafficking

项目摘要

项目成果

Bennet Andrew J的其他基金

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
Parkinson's disease (PD) is a worldwide health problem that has been linked to deficiencies in an enzyme called glucocerebrosidase (GCase). This enzyme plays a critical role in the body by breaking down a particular large molecule into two smaller, more e
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Design, synthesis and evaluation of potential neuraminidase inhibitors for the treatment of many conditions including influenza
海外基金