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Identifying the Cellular Mechanisms by which Inhibiting Ketone Body Oxidation Improves Glycemia in Obesity/Type 2 Diabetes

Identifying the Cellular Mechanisms by which Inhibiting Ketone Body Oxidation Improves Glycemia in Obesity/Type 2 Diabetes
确定抑制酮体氧化改善肥胖/2 型糖尿病血糖的细胞机制
批准号:
418730
负责人:
Ussher John Edward R
金额:
$81.37万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2020
资助国家:
加拿大
项目状态:
未结题
起止时间:
2020-03-01 至 2025-03-01

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中文摘要
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英文摘要
Our bodies rely on 3 major fuel sources we obtain from the food we eat; fats, sugars, and protein. However, during starvation our livers make a 4th fuel source that our organs (brain, heart, and muscle are the main users) can use to make energy, the keton
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Aging & Metabolic Flexibility
  • 批准号:
    468479
  • 项目类别:
    Operating Grants
  • 资助金额:
    $79.42万
  • 财政年份:
    2022
  • 负责人:
    Ussher John Edward R
  • 依托单位:
Discovery and Development of Brain-Sparing Inhibitors of Succinyl-CoA:3-Ketoacid CoA Transferase
  • 批准号:
    443699
  • 项目类别:
    Operating Grants
  • 资助金额:
    $65.48万
  • 财政年份:
    2021
  • 负责人:
    Ussher John Edward R
  • 依托单位:
Canada Research Chair - Tier 2
  • 批准号:
    415391
  • 项目类别:
  • 资助金额:
    $43.71万
  • 财政年份:
    2019
  • 负责人:
    Ussher John Edward R
  • 依托单位:
The GLP-1 Receptor & Myocardial Glucose Oxidation
  • 批准号:
    379538
  • 项目类别:
    Operating Grants
  • 资助金额:
    $70.5万
  • 财政年份:
    2018
  • 负责人:
    Ussher John Edward R
  • 依托单位:
海外基金