A strategy for expanding cell capabilities to sense their environment

扩展细胞感知环境能力的策略

• 批准号: 420054
• 负责人: Garton Michael J
• 金额: $ 55.45万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2020
• 资助国家: 加拿大
• 起止时间: 2020-03-01 至 2025-03-01
• 项目状态: 未结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=420054&lang=en
• 关键词: Cell-Based Therapy; Protein Design; Receptor Design; Synthetic Biology

Customized cell sensing of soluble molecules is one of the main challenges of cell design. Finding ways to do it would allow the engineering of therapeutic cells that autonomously sense engineer-specified disease or injury signals, and precisely deploy th

可溶性分子的定制细胞传感是细胞设计的主要挑战之一。找到这样做的方法将允许治疗性细胞的工程化，这些细胞能够自主感知工程师指定的疾病或损伤信号，并精确地部署细胞。