Microbiology of Nutrigenomics

营养基因组学微生物学

• 批准号: CRC-2018-00339
• 负责人: Willing, Benjamin
• 金额: $ 7.29万
• 依托单位: University of Alberta
• 依托单位国家: 加拿大
• 项目类别: Canada Research Chairs
• 财政年份: 2019
• 资助国家: 加拿大
• 起止时间: 2019-01-01 至 2020-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=692745
• 关键词: Microbiology; Nutrigenomics

There is a diverse population of microbes in the gut, and changes in this community have been associated with diverse health outcomes. Interventions such as early life exposures, diet, and antibiotic treatments allow correlation between changes in microbial abundance and behaviour, but often fail to show causal relationships. Dr. Willing is focused on showing causality of microbes in promoting health, and in some cases contributing to disease. By understanding how individual organisms contribute to the community and health outcome we can start to piece together this complex system.

肠道中有多种微生物，这个群体的变化与不同的健康结果有关。早期生活暴露、饮食和抗生素治疗等干预措施使微生物丰度变化与行为之间存在相关性，但往往无法显示因果关系。Willing博士专注于展示微生物在促进健康方面的因果关系，并在某些情况下导致疾病。通过了解个体生物如何对社区和健康结果做出贡献，我们可以开始拼凑这个复杂的系统。