Multi-user in vivo animal imaging system

温莎大学有越来越多的NSERC资助的年轻教师依靠成像来完成他们的研究项目。目前，整个温莎地区缺乏对整个动植物和组织进行荧光/发光成像的能力。获得一个核心设备的体内/离体成像仪，能够成像范围广泛的不同颜色和高质量的分辨率是绝对必要的，以促进研究和培训的成功，在本应用程序中描述的程序。在短期内，该设备将促进整个温莎大学理学院和工程学院的研究需求。因此，它所涵盖的科学领域是多种多样的；从细胞和分子生物学/生物化学/遗传学研究领域，如有机体如何发展，动物和植物细胞如何生长，分裂和调节正常和异常情况下的细胞死亡，免疫系统如何识别自我和非自我，到与动物如何处理声音有关的生理问题，以及这如何控制对外部环境的重要反应。计算机科学、物理和化学的课程依赖于体内药物可用性和荧光团可用性的评估，该设备将为MRI设备的新开发提供比较研究。总的来说，在温莎地区获得体内/离体成像能力将加速大量的研究项目，并将在未来6年内支持150多名HQP的培训和成功。

The University of Windsor has a growing number of NSERC funded young faculty dependent on imaging for their research programs. Currently, the entire Windsor region lacks any capacity for fluorescence/luminescence imaging of whole animals/plants and tissues. Acquisition of a core facility in vivo/ex vivo imager with capabilities to image a wide range of different colours with high quality resolution is absolutely essential to facilitate the success of the research and training of the programs described in this application. In the immediate term this equipment will facilitate the research needs of the entire Faculty of Science and Faculty of Engineering at the University of Windsor. Hence, the areas of science it encompasses are diverse; from cellular and molecular biology/biochemistry/genetics studying areas such as how organisms develop, how animal and plant cells grow, divide and regulate cell death in normal and abnormal situations, how the immune system recognizes self from non-self, to physiological questions relating to how animals process sound and how this controls important responses to the external environment. Programs in computer science, physics and chemistry rely on in vivo assessment of drug availability and fluorophore availability and this equipment will enable comparative studies for new development of MRI equipment. Collectively, obtaining in vivo/ex vivo imaging capacity in the Windsor region would accelerate a vast number of research projects and would support the training and success of more than 150 HQP in the next 6 years.