Polymeric Biomaterials

高分子生物材料

• 批准号: 1000233127-2019
• 负责人: Gillies, Elizabeth
• 金额: $ 10.93万
• 依托单位: University of Western Ontario
• 依托单位国家: 加拿大
• 项目类别: Canada Research Chairs
• 财政年份: 2020
• 资助国家: 加拿大
• 起止时间: 2020-01-01 至 2021-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=695115
• 关键词: Polymeric; Biomaterials

Polymers have immense potential to improve treatments for many diseases, but most research so far has focused on a limited subset of polymers. Dr. Gillies is developing materials with new properties and functions through innovative polymer design and synthesis. For example, she is developing polymers and coatings that can be triggered to degrade in specific conditions and using them to release therapeutics such as proteins, DNA, and antibiotics at the specific sites where they are needed in the body. She is also developing injectable delivery systems that can release drugs in joints in a sustained or disease-triggered manner.

聚合物在改善许多疾病的治疗方面具有巨大的潜力，但迄今为止大多数研究都集中在聚合物的有限子集上。吉利斯博士正在通过创新的聚合物设计和合成开发具有新特性和功能的材料。例如，她正在开发可以在特定条件下触发降解的聚合物和涂层，并利用它们在体内需要的特定部位释放蛋白质、DNA和抗生素等治疗药物。她还在开发可注射给药系统，该系统可以以持续或引发疾病的方式在关节中释放药物。