The UGT to GUS equilibrium as novel target for the treatment of cholestatic autoimmune liver diseases.
The UGT to GUS equilibrium as novel target for the treatment of cholestatic autoimmune liver diseases.
批准号:
435621
负责人:
Barbier Olivier
金额:
$69.94万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2020
资助国家:
加拿大
项目状态:
未结题
起止时间:
2020-10-01 至 2025-10-01
中文摘要
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英文摘要
Patients suffering from cholestatic and autoimmune liver diseases accumulate toxic bile acid in their liver. We know that these toxic molecules are converted in non toxic glucuronide forms (aka BA-G) in the liver by
detoxified in the liver by a series of
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